David P Hill

 ORCID
https://orcid.org/0000-0001-7476-6306
Affiliation
The Jackson Laboratory
Reviewed Pathways (69/69)
Date Identifier Pathway Reference
2026-01-21 R-HSA-6798163 Choline catabolism BibTex
2026-01-20 R-HSA-6798163 Choline catabolism BibTex
2025-10-24 R-HSA-6807047 Cholesterol biosynthesis via desmosterol (Bloch pathway) BibTex
2025-10-24 R-HSA-9969896 Lanosterol biosynthesis BibTex
2025-10-24 R-HSA-6807062 Zymostenol biosynthesis via lathosterol (Kandutsch-Russell pathway) BibTex
2025-10-24 R-HSA-9969901 Cholesterol biosynthesis from zymosterol (modified Kandutsch-Russell pathway) BibTex
2025-10-24 R-HSA-191273 Cholesterol biosynthesis BibTex
2025-06-16 R-HSA-9707564 Cytoprotection by HMOX1 BibTex
2025-06-02 R-HSA-70171 Glycolysis BibTex
2025-06-02 R-HSA-71387 Metabolism of carbohydrates and carbohydrate derivatives BibTex
2025-06-02 R-HSA-2022928 HS-GAG biosynthesis BibTex
2025-06-02 R-HSA-3322077 Glycogen synthesis BibTex
2025-06-02 R-HSA-1483206 Glycerophospholipid biosynthesis BibTex
2025-06-02 R-HSA-163685 Integration of energy metabolism BibTex
2025-05-30 R-HSA-6807062 Zymostenol biosynthesis via lathosterol (Kandutsch-Russell pathway) BibTex
2025-05-30 R-HSA-191273 Cholesterol biosynthesis BibTex
2025-05-28 R-HSA-196807 Nicotinate metabolism BibTex
2025-05-15 R-HSA-9939291 Matriglycan biosynthesis on DAG1 BibTex
2025-03-26 R-HSA-8964572 Lipid particle organization BibTex
2025-03-26 R-HSA-2564830 Cytosolic iron-sulfur cluster assembly BibTex
2025-03-26 R-HSA-5653890 Lactose synthesis BibTex
2025-03-26 R-HSA-5662702 Melanin biosynthesis BibTex
2025-02-26 R-HSA-446199 Synthesis of dolichyl-phosphate BibTex
2025-02-25 R-HSA-977347 Serine metabolism BibTex
2025-02-25 R-HSA-389661 Glyoxylate metabolism and glycine degradation BibTex
2025-02-25 R-HSA-70688 Proline catabolism BibTex
2025-02-25 R-HSA-71240 Tryptophan catabolism BibTex
2025-02-25 R-HSA-8849175 Threonine catabolism BibTex
2025-02-25 R-HSA-1614558 Degradation of cysteine and homocysteine BibTex
2024-08-02 R-HSA-390247 Beta-oxidation of very long chain fatty acids BibTex
2024-08-02 R-HSA-203615 eNOS activation BibTex
2024-08-02 R-HSA-2142816 Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) BibTex
2024-08-02 R-HSA-2142691 Synthesis of Leukotrienes (LT) and Eoxins (EX) BibTex
2024-08-02 R-HSA-2142670 Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) BibTex
2024-08-02 R-HSA-200425 Carnitine shuttle BibTex
2024-08-02 R-HSA-2142700 Biosynthesis of Lipoxins (LX) BibTex
2024-07-21 R-HSA-727802 Transport of nucleotide sugars BibTex
2024-07-19 R-HSA-727802 Transport of nucleotide sugars BibTex
2024-07-19 R-HSA-173599 Formation of the active cofactor, UDP-glucuronate BibTex
2024-05-22 R-HSA-9865881 Complex III assembly BibTex
2024-05-16 R-HSA-166187 Mitochondrial Uncoupling BibTex
2024-05-16 R-HSA-6799198 Complex I biogenesis BibTex
2024-05-16 R-HSA-9864848 Complex IV assembly BibTex
2024-05-16 R-SCE-9865878 Complex III assembly BibTex
2024-05-16 R-HSA-1428517 Aerobic respiration and respiratory electron transport BibTex
2024-05-15 R-HSA-446205 Synthesis of GDP-mannose BibTex
2024-03-01 R-HSA-70268 Pyruvate metabolism BibTex
2024-02-23 R-HSA-204174 Regulation of pyruvate dehydrogenase (PDH) complex BibTex
2024-02-23 R-HSA-9861718 Regulation of pyruvate metabolism BibTex
2024-02-23 R-HSA-9861559 PDH complex synthesizes acetyl-CoA from PYR BibTex
2024-02-20 R-HSA-9857492 Protein lipoylation BibTex
2024-02-20 R-HSA-1428517 Aerobic respiration and respiratory electron transport BibTex
2024-02-16 R-HSA-917937 Iron uptake and transport BibTex
2024-02-16 R-HSA-5655799 Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum) BibTex
2024-02-15 R-HSA-9856872 Malate-aspartate shuttle BibTex
2024-02-15 R-HSA-9853506 OGDH complex synthesizes succinyl-CoA from 2-OG BibTex
2024-02-15 R-HSA-9854311 Maturation of TCA enzymes and regulation of TCA cycle BibTex
2024-02-15 R-HSA-71403 Citric acid cycle (TCA cycle) BibTex
2024-02-15 R-HSA-611105 Respiratory electron transport BibTex
2024-02-12 R-HSA-163765 ChREBP activates metabolic gene expression BibTex
2023-11-08 R-HSA-177929 Signaling by EGFR BibTex
2023-07-26 R-HSA-199220 Vitamin B5 (pantothenate) metabolism BibTex
2023-07-26 R-HSA-196783 Coenzyme A biosynthesis BibTex
2022-08-29 R-HSA-70263 Gluconeogenesis BibTex
2022-05-19 R-HSA-174362 Transport and metabolism of PAPS BibTex
2022-02-14 R-HSA-196741 Cobalamin (Cbl, vitamin B12) transport and metabolism BibTex
2022-02-14 R-HSA-9758881 Uptake of dietary cobalamins into enterocytes BibTex
2022-02-14 R-HSA-9759218 Cobalamin (Cbl) metabolism BibTex
2022-02-14 R-HSA-9758890 Transport of RCbl within the body BibTex
Reviewed Reactions (562/562)
Date Identifier Reaction Reference
2026-01-20 R-HSA-6797956 SLC44A1 and SLC44A2 transport Cho from cytosol to mitochondrial matrix BibTex
2026-01-20 R-HSA-6797955 ALDH7A1 oxidises BETALD to BET BibTex
2026-01-20 R-HSA-6797957 SLC22A4 transports BET from mitochondrial matrix to cytosol BibTex
2026-01-20 R-HSA-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC BibTex
2026-01-20 R-HSA-6797913 SARDH:FAD oxidatively demethylates SARC to Gly BibTex
2025-12-16 R-HSA-1855173 5-PP-IP4 transports from the nucleus to the cytosol BibTex
2025-12-16 R-HSA-1855201 I(1,3,4,6)P4 transports from the cytosol to the nucleus BibTex
2025-12-16 R-HSA-1855161 I(1,3,4,5,6)P5 transports from the nucleus to the cytosol BibTex
2025-12-16 R-HSA-1855168 I(1,3,4,5)P4 transports from the cytosol to the nucleus BibTex
2025-12-16 R-HSA-1855190 I(1,4,5)P3 transports from the cytosol to the nucleus BibTex
2025-12-16 R-HSA-1855212 1/3-PP-IP5 transports from the cytosol to the nucleus BibTex
2025-12-16 R-HSA-1855188 IP6 transports from the cytosol to the nucleus BibTex
2025-12-16 R-HSA-1855203 5-PP-IP5 transports from the nucleus to the cytosol BibTex
2025-12-16 R-HSA-1855220 (PP)2-IP4 transports from the nucleus to the cytosol BibTex
2025-10-22 R-HSA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol BibTex
2025-10-09 R-HSA-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP BibTex
2025-10-08 R-HSA-6810594 HSD17B14 tetramer oxidises estradiol (EST17b) to estrone (E1) BibTex
2025-10-08 R-HSA-8862137 HSD17B2 oxidises estradiol (EST17b) to estrone (E1) BibTex
2025-10-08 R-HSA-5578744 Importin-8 imports AGO2:miRNA into the nucleus BibTex
2025-10-08 R-HSA-1855173 5-PP-IP4 transports from the nucleus to the cytosol BibTex
2025-10-08 R-HSA-1855201 I(1,3,4,6)P4 transports from the cytosol to the nucleus BibTex
2025-10-08 R-HSA-1855161 I(1,3,4,5,6)P5 transports from the nucleus to the cytosol BibTex
2025-10-08 R-HSA-1855168 I(1,3,4,5)P4 transports from the cytosol to the nucleus BibTex
2025-10-08 R-HSA-1855190 I(1,4,5)P3 transports from the cytosol to the nucleus BibTex
2025-10-08 R-HSA-1855212 1/3-PP-IP5 transports from the cytosol to the nucleus BibTex
2025-10-08 R-HSA-1855188 IP6 transports from the cytosol to the nucleus BibTex
2025-10-08 R-HSA-1855203 5-PP-IP5 transports from the nucleus to the cytosol BibTex
2025-10-08 R-HSA-1855220 (PP)2-IP4 transports from the nucleus to the cytosol BibTex
2025-08-28 R-HSA-170825 NPC exports GCK1 from nucleus BibTex
2025-08-28 R-HSA-170796 NPC transports GCK1:GCKR from cytosol to nucleoplasm BibTex
2025-08-14 R-HSA-6783883 P6C transforms to 2AMAS BibTex
2025-08-14 R-HSA-2855259 atROL binds RBP1 (parenchymal cell) BibTex
2025-08-13 R-HSA-1474158 GCHFR binds to GCH1 and negatively regulates its activity BibTex
2025-08-13 R-HSA-209738 VD3 binds GC BibTex
2025-08-13 R-HSA-209944 25(OH)D binds GC BibTex
2025-08-13 R-HSA-8963851 VD3 dissociates from GC BibTex
2025-08-13 R-HSA-350186 CUBN binds GC:25(OH)D BibTex
2025-08-13 R-HSA-350158 LGMN hydrolyzes GC, releasing CUBN and 25(OH)D BibTex
2025-08-13 R-HSA-8963915 1,25(OH)2D binds VDR BibTex
2025-08-13 R-HSA-8937177 AHR:TCDD binds ARNT BibTex
2025-08-13 R-HSA-8936849 AHR:2xHSP90:AIP:PTGES3 binds TCDD BibTex
2025-08-13 R-HSA-8937169 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm BibTex
2025-08-13 R-HSA-8937191 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 dissociates BibTex
2025-08-13 R-HSA-5340251 NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 BibTex
2025-08-13 R-HSA-8873850 STARD5 binds DCA, LCA BibTex
2025-08-13 R-HSA-2404135 RBP4 binds atROL BibTex
2025-08-13 R-HSA-2404142 atROL binds RBP1 BibTex
2025-08-13 R-HSA-2395764 atREs binds to nascent CM BibTex
2025-08-13 R-HSA-2399913 atRAL binds to RBP2 BibTex
2025-08-13 R-HSA-975633 atROL binds to RBP2 BibTex
2025-08-13 R-HSA-2423785 CR:atREs binds apoE and HSPG BibTex
2025-08-13 R-HSA-2404134 RBP4:atROL binds TTR BibTex
2025-08-13 R-HSA-5246478 APOM binds retinoids BibTex
2025-08-13 R-HSA-2161563 PGJ2 is isomerised to delta12-PGJ2 BibTex
2025-08-13 R-HSA-8848355 PNPLA4 hydrolyzes retinyl palmitate BibTex
2025-08-13 R-HSA-163402 diacylglycerol + H2O -> 2-acylglycerol + fatty acid BibTex
2025-08-13 R-HSA-163551 triacylglycerol + H2O -> diacylglycerol + fatty acid BibTex
2025-08-13 R-HSA-163549 phosphorylated HSL dimer + FABP4 -> phosphorylated HSL dimer:FABP4 complex BibTex
2025-08-13 R-HSA-163595 2-acylglycerol + H2O -> glycerol + fatty acid BibTex
2025-08-13 R-HSA-163432 cholesterol ester + H2O -> cholesterol + fatty acid BibTex
2025-08-13 R-HSA-8848339 PNPLA5 hydrolyzes TAG BibTex
2025-08-13 R-HSA-8848338 PNPLA4 hydrolyzes TAG BibTex
2025-08-13 R-HSA-5334794 FABPs bind LCFAs BibTex
2025-08-13 R-HSA-2065550 SREBP1A,1C,2 binds Importin beta-1 BibTex
2025-08-13 R-HSA-2065539 SREBP1A,1C,2:Importin beta-1 dissociates BibTex
2025-08-13 R-HSA-8862380 HSD17B13 binds lipid droplets BibTex
2025-08-13 R-HSA-6809254 MTMR8 binds MTMR9 BibTex
2025-08-13 R-HSA-8871366 p-Y389,400-RUFY1 binds RAB4A:GTP, RAB5:GTP, RAB14:GTP BibTex
2025-08-13 R-HSA-8871373 BMX phosphorylates RUFY1 BibTex
2025-08-13 R-HSA-6809793 MTMR2 binds SBF2 BibTex
2025-08-13 R-HSA-8871376 p-Y389,400-RUFY1 binds PI3P BibTex
2025-08-13 R-HSA-8870489 PLEKHA4,(5,6) bind PI3P BibTex
2025-08-13 R-HSA-8870499 PLEKHA3,8 bind PI4P, ARF1 BibTex
2025-08-13 R-HSA-6809309 MTMR6 binds MTMR9 BibTex
2025-08-13 R-HSA-8870332 PTPN13:PLEKHA1,2 bind PI(3,4)P2 BibTex
2025-08-13 R-HSA-400143 Fatty acid ligands activate PPARA BibTex
2025-08-13 R-HSA-400183 PPARA:RXRA binds Corepressors of PPARA BibTex
2025-08-13 R-HSA-400204 PPARA binds RXRA BibTex
2025-08-13 R-HSA-2026996 FABP1 transports fatty acids into the nucleus BibTex
2025-08-13 R-HSA-1855164 IP6 transports from the cytosol to the ER lumen BibTex
2025-08-13 R-HSA-1855195 I(1,3,4,5,6)P5 transports from the cytosol to the ER lumen BibTex
2025-08-13 R-HSA-1855155 I(1,3,4,5,6)P5 transports from the ER lumen to the cytosol BibTex
2025-08-13 R-HSA-9854672 FAD attaches to SDHA BibTex
2025-08-13 R-HSA-170810 nucleoplasmic GCK1:GCKR complex => glucokinase (GCK1) + glucokinase regulatory protein (GCKR) BibTex
2025-08-13 R-HSA-170824 glucokinase (GCK1) + glucokinase regulatory protein (GKRP) <=> GCK1:GKRP complex BibTex
2025-08-13 R-HSA-9854368 ROS,RNS oxidize ACO2:4Fe-4S BibTex
2025-08-13 R-HSA-9956909 CERT1-2 transfers CERA from the ER membrane to the Golgi membrane BibTex
2025-08-13 R-HSA-429730 PPM1L dephosphorylates multiphospho-CERT1-2 BibTex
2025-08-13 R-HSA-9842115 PSAP(195-273) dimer binds PE BibTex
2025-08-13 R-HSA-1614336 SUMF2 binds SUMF1, inhibiting SUMF1-mediated activation of arylsulfatases BibTex
2025-08-13 R-HSA-9663511 BIL binds GSTA1, FABP1 BibTex
2025-08-13 R-HSA-9661419 ALB binds extracellular heme BibTex
2025-08-13 R-HSA-190141 ALAD binds to Pb2+ BibTex
2025-08-13 R-HSA-2160915 Receptor-mediated uptake of HA BibTex
2025-08-13 R-HSA-174959 The acetyl group from acetyl-CoA is transferred to NAT1 BibTex
2025-08-13 R-HSA-158832 The acetyl group from acetyl-CoA is transferred to NAT2 BibTex
2025-08-13 R-HSA-196126 STAR mediates CHOL translocation from cytosol to mitochondrial intermembrane space BibTex
2025-08-13 R-HSA-9956308 STARD7 transports PC from ER membrane to mitochondrial outer membrane BibTex
2025-08-13 R-HSA-8873923 STARD10 binds LPCAT1 and PC BibTex
2025-08-13 R-HSA-8873794 PCTP binds PC BibTex
2025-08-13 R-HSA-8873834 STARD10 transports PC from ER membrane to lamellar body membrane BibTex
2025-08-12 R-HSA-9960428 2AMAS transport from peroxisome to mitochondrial matrix BibTex
2025-08-12 R-HSA-9955574 ODC dimerizes BibTex
2025-08-12 R-HSA-9856737 Unknown enzyme(s) process 4-HMA to 4-Hbz BibTex
2025-08-12 R-HSA-1678694 Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans BibTex
2025-08-12 R-HSA-8940134 FOLR2 binds FOLA BibTex
2025-08-12 R-HSA-193715 5beta-cholestan-3alpha,7alpha,24(S)-triol is translocated from the cytosol to the mitochondrial matrix BibTex
2025-08-12 R-HSA-192010 5beta-cholestan-3alpha, 7alpha, 12alpha-triol is translocated from the cytosol to the mitochondrial matrix BibTex
2025-08-12 R-HSA-193808 5beta-cholestan-3alpha,7alpha,27-triol is translocated from the cytosol to the mitochondrial matrix BibTex
2025-08-12 R-HSA-193537 5beta-cholestan-3alpha, 7alpha-diol is translocated from the cytosol to the mitochondrial matrix BibTex
2025-08-12 R-HSA-193774 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is translocated from the cytosol to the mitochondrial matrix BibTex
2025-08-12 R-HSA-193832 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is translocated from the cytosol to the mitochondrial matrix BibTex
2025-08-12 R-HSA-6809238 MTMR7 binds MTMR9 BibTex
2025-08-12 R-HSA-8866941 MID1IP1 binds THRSP BibTex
2025-08-12 R-HSA-5333678 CPNEs bind PL BibTex
2025-08-12 R-HSA-6809764 SBF1 binds MTMR2 BibTex
2025-08-12 R-HSA-8874705 TTPA transports alpha-TOH from lysosomal membrane to plasma membrane BibTex
2025-06-16 R-HSA-2160892 HYAL2 hydrolyses HA into 20kDa fragments BibTex
2025-06-16 R-HSA-350567 Antizyme OAZ binds to Ornithine decarboxylase BibTex
2025-06-16 R-HSA-400204 PPARA binds RXRA BibTex
2025-06-16 R-HSA-1855217 I(1,4,5)P3 transports from the ER lumen to the cytosol BibTex
2025-06-16 R-HSA-1855186 I(1,3,4,5)P4 transports from the cytosol to the ER lumen BibTex
2025-06-16 R-HSA-8878815 Formation of 4Fe-4S cluster on ISCA1:ISCA2 BibTex
2025-06-16 R-HSA-1362416 Frataxin binds iron BibTex
2025-06-16 R-HSA-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) BibTex
2025-06-16 R-HSA-2395517 NADPH transfers electrons to FDXR BibTex
2025-06-16 R-HSA-9661432 BIL binds ALB BibTex
2025-06-02 R-HSA-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP BibTex
2025-06-02 R-HSA-453342 PYGM dimer, b form + 2 AMP => PYGM b dimer:AMP complex BibTex
2025-06-02 R-HSA-453356 PYGB dimer, b form + 2 AMP => PYGB b dimer:AMP complex BibTex
2025-06-02 R-HSA-453337 glycogen phosphorylase (PYGB) dimer b + 2 ATP => glycogen phosphorylase (PYGB) dimer a + 2 ADP BibTex
2025-06-02 R-HSA-197268 QPRT transfers PRIB to QUIN to form NAMN BibTex
2025-06-02 R-HSA-197187 ACS transforms to QUIN non-enzymatically BibTex
2025-06-02 R-HSA-197250 NAMPT transfers PRIB to NAM to form NAMN BibTex
2025-06-02 R-HSA-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD BibTex
2025-06-02 R-HSA-197271 NADSYN1 hexamer amidates NAAD to NAD+ BibTex
2025-06-02 R-HSA-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ BibTex
2025-06-02 R-HSA-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD BibTex
2025-06-02 R-HSA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN BibTex
2025-06-02 R-HSA-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD BibTex
2025-06-02 R-HSA-169680 IP3 binds to the IP3 receptor, opening the endoplasmic reticulum Ca2+ channel BibTex
2025-06-02 R-HSA-163688 Dephosphorylation of pChREBP (Thr 666) by PP2A BibTex
2025-06-02 R-HSA-1676152 PI4KB binds to ARF1/3:GTP at the Golgi membrane BibTex
2025-06-02 R-HSA-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate BibTex
2025-06-02 R-HSA-400434 FFAR1 binds fatty acids BibTex
2025-06-02 R-HSA-434381 CD36 (FAT) translocates a long chain fatty acid from the extracellular region to the cytosol BibTex
2025-06-02 R-HSA-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to a long chain fatty acid yielding fatty acyl-coenzyme A BibTex
2025-06-02 R-HSA-9673054 PM20D1 hydrolyzes oleoyl-phe BibTex
2025-06-02 R-HSA-9673053 PM20D1 transforms oleoyl-phe from oleate and phe BibTex
2025-06-02 R-HSA-381713 Potassium voltage-gated channels close in reponse to PKA BibTex
2025-06-02 R-HSA-381644 ER calcium channels open in response to activated PKA BibTex
2025-06-02 R-HSA-381727 RAP1A exchanges GDP for GTP BibTex
2025-06-02 R-HSA-400046 L-type Calcium Channels close in pancreatic beta cells BibTex
2025-06-02 R-HSA-400063 Low conductance potassium channels in pancreatic beta cells open in response to epinephrine BibTex
2025-06-02 R-HSA-163689 PP2A complex dephosphorylates pChREBP (MLXIPL) BibTex
2025-05-30 R-HSA-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate BibTex
2025-05-30 R-HSA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL BibTex
2025-05-30 R-HSA-9945804 HSD17B7 reduces 5a-cholest-8-en-3-one to ZYMSTNL BibTex
2025-05-30 R-HSA-9945787 NSDHL decarboxylates 4a-carboxy-5a-cholest-8-ene-3b-ol to 5a-cholest-8-en-3-one BibTex
2025-05-30 R-HSA-9947207 MSMO1 oxidizes 4a-me-5a-cholest-8-en-3b-ol to 4a-carboxy-5a-cholest-8-ene-3b-ol BibTex
2025-05-30 R-HSA-9945784 HSD17B7 reduces 4a-methyl-5a-cholest-8-en-3-one to 4a-methyl-5a-cholest-8-en-3b-ol BibTex
2025-05-30 R-HSA-9945822 NSDHL decarboxylates 4a-carboxy-4b-methyl-5a-cholest-8-en-3b-ol to 4a-methyl-5a-cholest-8-en-3b-ol BibTex
2025-05-30 R-HSA-9947203 MSMO1 oxidizes 4,4-diMe-5-cholest-8-en-3-ol to 4a-carboxy-4b-me-5a-cholest-8-en-3b-ol BibTex
2025-05-30 R-HSA-9946140 TM7SF2 reduces 4,4-diMeCholesta-8,14-dien-3-ol to 4,4-diMe5-cholest-8-en-3-ol BibTex
2025-05-30 R-HSA-9947148 CYP51A1 14-demethylates 24,25-dhLAN to 4,4-diMeCholesta-8,14-dien-3-ol BibTex
2025-05-30 R-HSA-76494 POR reduces CYP450:Fe3+ to CYP450:Fe2+ BibTex
2025-05-30 R-HSA-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one BibTex
2025-05-30 R-HSA-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate BibTex
2025-05-28 R-HSA-163750 PP2A complex dephosphorylates pPFKFB1 BibTex
2025-05-28 R-HSA-163625 Glucagon binds to Glucagon receptor BibTex
2025-05-23 R-HSA-9948070 POMGNT1 catalyzes FKRP:FKTN:RXYLT1 formation BibTex
2025-05-15 R-HSA-9948070 POMGNT1 catalyzes FKRP:FKTN:RXYLT1 formation BibTex
2025-05-15 R-HSA-9940735 FKTN transfers RboP to GalNAc-GlcNAc-ManP-DAG1 BibTex
2025-03-26 R-HSA-8856630 CIDEA:CIDEC binds lipid droplets BibTex
2025-03-26 R-HSA-8857686 FITM2 binds TAGs BibTex
2025-03-26 R-HSA-8858270 HILPDA binds lipid droplets BibTex
2025-03-26 R-HSA-9942190 FITM1 binds TAGs BibTex
2025-03-26 R-HSA-8862380 HSD17B13 binds lipid droplets BibTex
2025-03-26 R-HSA-2564824 NADPH reduces NDOR1:CIAPIN1 BibTex
2025-03-26 R-HSA-5653886 B4GALT1 binds LALBA BibTex
2025-03-26 R-HSA-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac BibTex
2025-03-26 R-HSA-5662662 Tyrosinase oxidises tyrosine to dopaquinone BibTex
2025-03-26 R-HSA-5662692 Dopa is oxidized to dopaquinone by TYR BibTex
2025-03-26 R-HSA-8878581 TYRP1 oxidises DHICA to IQCA BibTex
2025-03-04 R-HSA-446195 DOLK phosphorylates DCHOL to DOLP BibTex
2025-03-04 R-HSA-446200 DOLPP1 dephosphorylates DOLDP to DOLP BibTex
2025-02-27 R-HSA-9929460 SDS dimers:PXLP convert L-Ser to PYR and NH4+ BibTex
2025-02-27 R-HSA-9773976 AKR1E2 reduces 1,5-aF to 1,5-aG BibTex
2025-02-27 R-HSA-9929439 ALDH4A1 oxidizes 1PYR-3OH-5COOH BibTex
2025-02-26 R-HSA-446195 DOLK phosphorylates DCHOL to DOLP BibTex
2025-02-26 R-HSA-9937340 DHRSX reduces dolichal to dolichol BibTex
2025-02-26 R-HSA-9937295 SRD5A3 reduces polyprenal to dolichal BibTex
2025-02-26 R-HSA-9937298 DHRSX oxidizes polyprenol to polyprenal BibTex
2025-02-26 R-HSA-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP BibTex
2025-02-26 R-HSA-8955794 PGP:Mg2+ dimer hydrolyses G3P to glycerol BibTex
2025-02-25 R-HSA-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 BibTex
2025-02-25 R-HSA-9858590 DLST transfers glutaryl to CoA BibTex
2025-02-25 R-HSA-8954513 NAASP translocates from mitochondrial matrix to cytosol BibTex
2025-02-25 R-HSA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ BibTex
2025-02-25 R-HSA-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P BibTex
2025-02-25 R-HSA-9035484 MPST and TXN2 enable the synthesis of disulfanide from CysS248-MPST BibTex
2025-02-25 R-HSA-1655879 Thiosulfate can transfer its sulfur atom to glutathione BibTex
2025-02-25 R-HSA-1614591 Excess cysteine yields lanthionine and H2S BibTex
2025-02-25 R-HSA-1614583 PXLP-K212-CTH cleaves L-Cystathionine BibTex
2025-02-25 R-HSA-1237119 Acireductone is oxidized to MOB BibTex
2025-02-25 R-HSA-1237129 Acireductone is created BibTex
2025-02-25 R-HSA-1614614 Cysteine is degraded to pyruvate and H2S BibTex
2025-02-25 R-HSA-1614567 Excess homocysteine yields homolanthionine and H2S BibTex
2025-02-25 R-HSA-1614631 Homocysteine is degraded to oxobutanoate and H2S BibTex
2025-02-25 R-HSA-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL BibTex
2025-02-25 R-HSA-8955817 PRODH2 oxidises HPRO to 1PYR-3OH-5COOH BibTex
2025-02-25 R-HSA-70670 PRODH oxidises L-Pro to 1PYR-5COOH BibTex
2025-02-25 R-HSA-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate BibTex
2025-02-25 R-HSA-6784402 ALDH4A1 converts 1PYR-3OH-5COOH to 4-OH-L-glutamate BibTex
2025-02-25 R-HSA-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) BibTex
2025-02-25 R-HSA-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF BibTex
2025-02-25 R-HSA-5693967 PXLP-K754-GLDC dimer decarboxylates Gly BibTex
2025-02-25 R-HSA-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC BibTex
2025-02-25 R-HSA-9014741 PXLP-K56-SRR dimer deaminates D-Ser BibTex
2025-02-25 R-HSA-2160492 IL4I1:FAD oxidises L-Phe to kPPV BibTex
2025-02-25 R-HSA-893593 phenylalanine + pyruvate => keto-phenylpyruvate + alanine BibTex
2025-02-25 R-HSA-5333612 MeSebGalNac is oxidatively cleaved to MeSeO2H and 2-acetamidoglucal BibTex
2025-02-25 R-HSA-5333608 GSSebGalNac is reduced and methylated to MeSebGalNac BibTex
2025-02-25 R-HSA-5333607 GSSeH combines with bGalNAc derivative to form GSSebGalNac BibTex
2025-02-25 R-HSA-2408556 SeO3(2-) combines with GSH to form GSSeSG and GSSG BibTex
2025-02-25 R-HSA-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer BibTex
2025-02-25 R-HSA-2408543 SeCysta is hydrolysed to Sec by PXLP-K212-CTH BibTex
2025-02-25 R-HSA-2408544 AdoSeMet is converted to AdeSeHCys by MetTrans(1) BibTex
2025-02-25 R-HSA-5333609 MeSebGalNac is hydrolysed to MeSeH and bGalNac BibTex
2025-02-25 R-HSA-2408537 Excess SeMet is cleaved into MeSeH by PXLP-K212-CTH BibTex
2025-02-25 R-HSA-2408539 MeSec is hydrolysed to MeSeH by PXLP-K212-CTH BibTex
2025-02-25 R-RNO-2408538 MeSec is hydrolysed to MeSeH by PXLP-K211-Cth BibTex
2025-02-25 R-HSA-8959510 SEPHS2 phosphorylates H2Se to form SELP BibTex
2025-02-25 R-HSA-2408529 Sec-tRNA(Sec):EEFSEC:GTP binds to 80S Ribosome BibTex
2025-02-25 R-HSA-2408509 Sec-tRNA(Sec) binds to EEFSEC:GTP BibTex
2025-02-25 R-HSA-2408555 Sep-tRNA(Sec) is converted to Sec-tRNA(Sec) by PXLP-K284-SEPSECS tetramer BibTex
2025-02-25 R-HSA-2408526 tRNA(Sec) is serylated to Ser-tRNA(Sec) by SARS dimer BibTex
2025-02-25 R-HSA-70679 ALDH4A1 oxidises L-GluSS to Glu BibTex
2025-02-25 R-HSA-71189 AFMID hydrolyses NFK to L-KYN BibTex
2025-02-25 R-HSA-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine + H+ BibTex
2025-02-25 R-HSA-893596 PXLP-KYAT1 dimer transaminates L-KYN to KYNA BibTex
2025-02-25 R-HSA-71223 2-amino-3-carboxymuconate semialdehyde => 2-aminomuconate semialdehyde + CO2 BibTex
2025-02-25 R-HSA-901097 PXLP-KYAT3 (CCBL2) dimer transaminates L-KYN to KYNA BibTex
2025-02-25 R-HSA-9014641 HRSP12 deaminates 2-iminobutanoate to 2OBUTA BibTex
2025-02-25 R-HSA-9014627 SDS dimers:PXLP convert L-Thr to 2OBUTA BibTex
2025-02-25 R-HSA-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN BibTex
2025-02-25 R-HSA-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU BibTex
2025-02-25 R-HSA-1655453 FMO1:FAD oxidizes HTAU to TAU BibTex
2025-02-25 R-HSA-1655443 PXKLP-K305-CSAD decarboxylates 3-sulfinoalanine to hypotaurine BibTex
2025-02-25 R-HSA-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine BibTex
2024-11-19 R-HSA-200729 SLC46A1 transports FOLA from extracellular region to cytosol BibTex
2024-11-19 R-HSA-200646 Cytosolic folate export across the plasma membrane BibTex
2024-08-02 R-HSA-428990 SLC27A1 transports arachidonate across the ER membrane BibTex
2024-08-02 R-HSA-111883 PLA2G4A (cPLA2) hydrolyzes phosphatidylcholine BibTex
2024-08-02 R-HSA-111881 Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase BibTex
2024-08-02 R-MMU-9915559 Slc27a1 transports arachidonate across the ER membrane BibTex
2024-08-02 R-HSA-3159259 MMAA:MUT binds AdoCbl BibTex
2024-08-02 R-HSA-3149563 MMADHC targets transport of cytosolic cob(II)alamin to mitochondria BibTex
2024-08-02 R-HSA-70893 methylmalonate semialdehyde + NAD+ + CoA + H2O => propionyl-CoA + HCO3- + NADH + H+ BibTex
2024-08-02 R-HSA-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA BibTex
2024-08-02 R-HSA-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 BibTex
2024-08-02 R-HSA-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 BibTex
2024-08-02 R-HSA-390393 Peroxisomal uptake of very long-chain fatty acyl CoA BibTex
2024-08-02 R-HSA-9914143 SLC27A2-mediated ligation of peroxisomal fatty acid and CoASH BibTex
2024-08-02 R-HSA-70773 beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) BibTex
2024-08-02 R-HSA-8848247 ACBD4,5 bind MCFA-CoA and LCFA-CoA BibTex
2024-08-02 R-HSA-6786720 DECR2 reduces a (2E,4E)-dienoyl-CoA to a 4,5-saturated-(3E)-enoyl-CoA BibTex
2024-08-02 R-HSA-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome BibTex
2024-08-02 R-HSA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA BibTex
2024-08-02 R-HSA-389609 ALDH3A2-2 oxidizes pristanal to pristanate BibTex
2024-08-02 R-HSA-390276 Conversion of 4,8,12-trimethyltridecanoyl-CoA to 4,8-dimethylnonanoyl-CoA BibTex
2024-08-02 R-HSA-390304 acetyl-CoA + H2O => acetate + CoASH + H+ BibTex
2024-08-02 R-HSA-6809354 NUDT7 hydrolyses CoA-SH to 3',5'-ADP and PPANT BibTex
2024-08-02 R-HSA-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT BibTex
2024-08-02 R-HSA-9911362 CPT1B transfers PALM to CAR BibTex
2024-08-02 R-HSA-203613 Depalmitoylation of eNOS BibTex
2024-08-02 R-HSA-203567 Palmitoylation of eNOS BibTex
2024-08-02 R-HSA-203611 N-myristoylation of eNOS BibTex
2024-08-02 R-HSA-1497796 BH2 binding can lead to eNOS uncoupling BibTex
2024-08-02 R-HSA-202127 eNOS synthesizes NO BibTex
2024-08-02 R-HSA-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle BibTex
2024-08-02 R-HSA-202111 AKT1 phosphorylates eNOS BibTex
2024-08-02 R-HSA-202137 AKT1 binds eNOS complex via HSP90 BibTex
2024-08-02 R-HSA-202144 Caveolin-1 dissociates from eNOS:CaM:HSP90 complex BibTex
2024-08-02 R-HSA-202129 HSP90 binds eNOS:Caveolin-1:CaM complex BibTex
2024-08-02 R-HSA-202110 eNOS:Caveolin-1 complex binds to CaM BibTex
2024-08-02 R-HSA-203712 eNOS associates with Caveolin-1 BibTex
2024-08-02 R-HSA-5340226 CYGB dioxygenates NO BibTex
2024-08-02 R-HSA-203553 eNOS binds NOSIP BibTex
2024-08-02 R-HSA-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments BibTex
2024-08-02 R-HSA-203716 eNOS:Caveolin-1 complex binds to Nostrin BibTex
2024-08-02 R-HSA-203565 eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP BibTex
2024-08-02 R-HSA-203662 eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2 BibTex
2024-08-02 R-HSA-5340195 NR1H4 binds DCA, CDCA, LCHA BibTex
2024-08-02 R-HSA-193101 CYP11A1 cleaves 20a,22b-DHCHOL BibTex
2024-08-02 R-HSA-266070 LTC4 is exported from the cytosol by ABCC1 BibTex
2024-08-02 R-HSA-429016 ALOX5 is phosphorylated by MAPKAP2 BibTex
2024-08-02 R-HSA-1449687 Corticosteroids bind to CBG in blood BibTex
2024-08-02 R-HSA-193997 CYP11B1 oxidises 11DCORT BibTex
2024-08-02 R-HSA-193060 CYP19A1 hydroxylates ANDST to E1 BibTex
2024-08-02 R-HSA-194017 CYP11B2 oxidises 11DCORST to CORST BibTex
2024-08-02 R-HSA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST BibTex
2024-08-02 R-HSA-193965 CYP11B2 oxidises 18HCORST to ALDO BibTex
2024-08-02 R-HSA-140359 PGG2 is reduced to PGH2 by PTGS1 BibTex
2024-08-02 R-HSA-2309773 PGG2 is reduced to PGH2 by PTGS2 BibTex
2024-08-02 R-HSA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids BibTex
2024-08-02 R-HSA-5433066 Unknown NAT transfers COCH3 to AFXBO-C, AFNBO-C BibTex
2024-08-02 R-HSA-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids BibTex
2024-08-02 R-HSA-2161659 PGE2 is dehydrated to PGA2 BibTex
2024-08-02 R-HSA-2161666 PGA2 is isomerised to PGC2 BibTex
2024-08-02 R-HSA-2161735 PGC2 is isomerised to PGB2 BibTex
2024-08-02 R-HSA-9716836 PTGS2 dimer binds PTGS inhibitors BibTex
2024-08-02 R-HSA-9716838 PTGS1,2 dimers bind PTGS Inhibitors BibTex
2024-08-02 R-HSA-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) BibTex
2024-08-02 R-HSA-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) BibTex
2024-08-02 R-HSA-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) BibTex
2024-08-02 R-HSA-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) BibTex
2024-08-02 R-HSA-9915986 11,12-EET is hydrolysed to 11,12-DHET by EPHX2 BibTex
2024-08-02 R-HSA-9915968 8,9-EET is hydrolysed to 8.9-DHET by EPHX2 BibTex
2024-08-02 R-HSA-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) BibTex
2024-08-02 R-HSA-2161961 5,6-EET is hydrolysed to 5,6-DHET by EPHX2 BibTex
2024-08-02 R-HSA-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) BibTex
2024-08-02 R-HSA-9915994 14,15-EET is hydrolysed to 14,15-DHET by EPHX2 BibTex
2024-08-02 R-HSA-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis BibTex
2024-08-02 R-HSA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA BibTex
2024-08-02 R-HSA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA BibTex
2024-08-02 R-HSA-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 BibTex
2024-08-02 R-HSA-2161775 ALOX12 oxidises LTA4 to LXA4 BibTex
2024-08-02 R-HSA-2161844 15k-LXA4 is reduced to dhk-LXA4 by PTGR1 BibTex
2024-08-02 R-SSC-2161847 15k-LXA4 is reduced to dhk-LXA4 by PTGR1 BibTex
2024-08-02 R-HSA-9916401 ALOX12 oxidises LTA4 to LXB4 BibTex
2024-08-02 R-HSA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 BibTex
2024-08-02 R-HSA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 BibTex
2024-08-02 R-HSA-9027532 PTGS2 dimer oxidises DHA to 13-HDHA BibTex
2024-08-02 R-HSA-9032323 oxo-DPAn-3s translocate from cytosol to extracellular region BibTex
2024-08-02 R-HSA-9032327 5-oxo-EPA, 15d-PGJ3 translocate from cytosol to extracellular region BibTex
2024-08-02 R-HSA-9032315 oxo-DHAs translocate from cytosol to extracellular region BibTex
2024-08-02 R-HSA-9018901 5-HEDH dehydrogenates 5(S)-Hp-18(R)-HEPE to 18(R)-RvE2 BibTex
2024-08-02 R-HSA-9018867 5-HEDH dehydrogenates 5(S)-Hp-18(S)-HpEPE to 18(S)-RvE2 BibTex
2024-07-19 R-HSA-3149494 MMACHC:cob(II)alamin binds MMADHC BibTex
2024-07-19 R-HSA-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin BibTex
2024-07-19 R-HSA-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR BibTex
2024-07-19 R-HSA-173597 UDP-glucose is oxidised to UDP-glucuronate BibTex
2024-07-19 R-HSA-70286 UTP + D-glucose 1-phosphate => pyrophosphate + UDP-glucose BibTex
2024-07-19 R-HSA-9912889 SLC35D2 exchanges UDP-GlcA for UMP BibTex
2024-05-24 R-HSA-9866162 Late core complex dimerizes BibTex
2024-05-24 R-SCE-9866165 Late core complex dimer binds QCR9. QCR10, RIP1 BibTex
2024-05-16 R-HSA-9866217 HCCS inserts heme into cytochrome c BibTex
2024-05-16 R-HSA-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to CoQH2 BibTex
2024-05-16 R-HSA-164651 Electron transfer from ubiquinol to cytochrome c of complex III BibTex
2024-05-16 R-HSA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 BibTex
2024-05-16 R-HSA-163214 Electron transfer from reduced cytochrome c to molecular oxygen BibTex
2024-05-16 R-HSA-163213 Transfer of electrons through the succinate dehydrogenase complex BibTex
2024-05-16 R-HSA-170026 UCP1 imports a proton BibTex
2024-05-16 R-HSA-9864415 AAC1 imports a proton BibTex
2024-05-16 R-HSA-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 BibTex
2024-05-16 R-HSA-6788523 NUBPL transfers 4Fe-4S to Complex I subunits BibTex
2024-05-16 R-HSA-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex BibTex
2024-05-16 R-HSA-6799178 Intermediate 1 binds HP subcomplex to form Intermediate 2 BibTex
2024-05-16 R-HSA-6799199 COA1:MT-ND2, TMEM186:MT-ND3, MT-ND6, NDUFB6 bind the MCIA complex to form a 370kDa subcomplex BibTex
2024-05-16 R-HSA-6799197 ND4, ND5 bind the 550kDa complex to form the 815kDa complex BibTex
2024-05-16 R-HSA-9906955 MT-ND4 is translated BibTex
2024-05-16 R-HSA-9865350 Nascent MT-CO1 binds to MITRAC, Mg2+, PE, CL BibTex
2024-05-16 R-HSA-9865663 MT-CO3, COX6A,B,7A and NDUFA4 bind to holo-MT-CO1,2 complex BibTex
2024-05-16 R-HSA-9865579 MT-CO1 and MT-CO2 complexes associate, installing heme moieties BibTex
2024-05-16 R-HSA-9865569 MT-CO2 mRNA is translated BibTex
2024-05-16 R-HSA-9865630 Metallochaperone inserts 2Cu2+ into MT-CO2 BibTex
2024-05-16 R-HSA-9902096 COX18 inserts nascent MT-CO2 in COX20:TMEM77 BibTex
2024-05-16 R-HSA-9865449 Metallochaperone inserts Cu2+ into MT-CO1 BibTex
2024-05-16 R-HSA-9865412 TIMM21 carries COX4, COX5A, COX6C to MT-CO1:MITRAC BibTex
2024-05-16 R-HSA-9865309 MT-CO1 mRNA is translated BibTex
2024-05-16 R-HSA-9866272 2Fe-2S is inserted in UQCRFS1 BibTex
2024-05-16 R-HSA-9866253 apo-UQCRFS1 binds LYRM7 BibTex
2024-05-16 R-HSA-9906042 TTC19 clears UQCRFS1 fragments from Complex III BibTex
2024-05-16 R-HSA-9906017 Unknown peptidase cleaves UQCRFS1 subunit BibTex
2024-05-16 R-HSA-9866164 Late core complex dimer binds UQCR10, UQCR11, UQCRFS1. BibTex
2024-05-16 R-HSA-9866132 Intermediate II binds CYC1, UQCRC1, UQCRC2, UQCRH BibTex
2024-05-16 R-HSA-9866104 Intermediate I binds second heme, UQCRB, UQCRQ BibTex
2024-05-16 R-HSA-9866061 Intermediate 0 binds heme and UQCC3 BibTex
2024-05-16 R-HSA-9865893 MT-CYB is translated BibTex
2024-05-16 R-SCE-9865912 CYTB is translated BibTex
2024-05-16 R-SCE-9866071 CYTB binds heme and CBP4 BibTex
2024-05-16 R-SCE-9866108 CYTB binds second heme, QCR7, QCR8 BibTex
2024-05-16 R-SCE-9866128 CYTB:QCR7:QCR8 binds CYT1, COR1, COR2, QCR6 BibTex
2024-05-16 R-SCE-9866173 Late core complex dimerizes BibTex
2024-05-15 R-HSA-9909159 HK1 phosphorylates Mannose to Man6P BibTex
2024-05-15 R-HSA-532549 MPI isomerises Fru6P to Man6P BibTex
2024-05-15 R-HSA-446201 PMM1,2 isomerise Man6P to Man1P BibTex
2024-05-15 R-HSA-446221 GMPPB converts Mannose-1-phosphate to GDP-Mannose BibTex
2024-04-12 R-HSA-163756 Formation of fatty acid synthase (FAS) dimer BibTex
2024-04-12 R-HSA-200555 Formation of Malonyl-CoA from Acetyl-CoA (liver) BibTex
2024-04-12 R-HSA-5690517 PPT1 hydrolyses palmitoylated proteins BibTex
2024-04-12 R-HSA-5655955 OLAH hydrolyzes decanoyl-FASN dimer to DECA and FASN dimer BibTex
2024-04-12 R-HSA-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA BibTex
2024-04-12 R-HSA-548830 ELOVL1,4 elongate TCS-CoA and Mal-CoA to 3OHC-CoA BibTex
2024-04-12 R-MMU-548848 lignoceroyl-CoA + malonyl-CoA => 3-oxocerotoyl-CoA + CO2 + CoASH [Elovl4] BibTex
2024-04-12 R-HSA-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA BibTex
2024-04-12 R-HSA-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA BibTex
2024-04-12 R-HSA-5690046 PPT2 hydrolyses PALMCoA to PALM BibTex
2024-04-12 R-HSA-9734540 ACLY tetramer binds ETC-1002-CoA BibTex
2024-04-04 R-HSA-194017 CYP11B2 oxidises 11DCORST to CORST BibTex
2024-04-04 R-HSA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST BibTex
2024-04-04 R-HSA-193965 CYP11B2 oxidises 18HCORST to ALDO BibTex
2024-03-01 R-HSA-9863531 GS-MCA spontaneously hydrolyzes BibTex
2024-02-23 R-HSA-9012268 ME2 tetramer decarboxylates MAL to PYR BibTex
2024-02-23 R-HSA-9012349 ME3 tetramer decarboxylates MAL to PYR BibTex
2024-02-23 R-HSA-203946 PDK isozymes phosphorylate PDHC subunit E1 BibTex
2024-02-23 R-HSA-9861667 DLAT trimer transfers acetyl to CoA BibTex
2024-02-23 R-HSA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT BibTex
2024-02-23 R-HSA-372342 MPC1:MPC2 imports PYR, H+ to mitochondrial matrix BibTex
2024-02-23 R-HSA-71670 Pyruvate kinase dephosphorylates PEP to PYR BibTex
2024-02-23 R-HSA-70501 PC carboxylates PYR to OA BibTex
2024-02-23 R-HSA-9012016 FAHD1 dimer hydrolyses OA to PYR BibTex
2024-02-23 R-HSA-204169 PDP1,2 dephosphorylate p-lipo-PDH BibTex
2024-02-23 R-HSA-9861616 DLD dimer dehydrogenates dihydrolipoyl BibTex
2024-02-23 R-HSA-6807826 LDHAL6B reduces PYR to LACT BibTex
2024-02-23 R-HSA-70523 PXLP-K314-GPT transaminates L-Ala to form PYR BibTex
2024-02-23 R-HSA-70510 LDH tetramer oxidises LACT to PYR BibTex
2024-02-23 R-HSA-71849 LDH tetramer reduces PYR to LACT BibTex
2024-02-23 R-HSA-9861660 ME1 tetramer decarboxylates OA to PYR BibTex
2024-02-23 R-HSA-9861631 ME1 tetramerizes BibTex
2024-02-23 R-HSA-9861725 PGAM5 dodecamer dephosphorylates p-S336-ME1 BibTex
2024-02-23 R-HSA-9861642 NEK1 phosphorylates ME1 BibTex
2024-02-23 R-HSA-9012036 ME1 tetramer decarboxylates MAL to PYR BibTex
2024-02-23 R-HSA-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space BibTex
2024-02-23 R-HSA-9011543 DCA binds PDK2 BibTex
2024-02-23 R-HSA-9011595 GSTZ1 dimer dehalogenates DCA BibTex
2024-02-23 R-HSA-9861626 SIRT4 cleaves lipoyl from DLAT BibTex
2024-02-23 R-HSA-9861563 CTLH E3 ligase ubiquitinates LDHA BibTex
2024-02-23 R-HSA-9861640 CTLH E3 ligase ubiquitinates PKM-1 BibTex
2024-02-23 R-HSA-9861745 Mitochondrial H2O2 decarboxylates PYR to acetate BibTex
2024-02-23 R-HSA-9861595 Cytosolic H2O2 decarboxylates PYR to acetate BibTex
2024-02-20 R-HSA-6792572 LIPT1 transfers lipoyl group from lipoyl-GCSH to DBT/DLST BibTex
2024-02-20 R-HSA-6793591 LIAS synthesizes lipoyl-GCSH BibTex
2024-02-20 R-HSA-6793590 LIPT2 transfers octanoyl group to GCSH BibTex
2024-02-20 R-HSA-9858752 LIPT1 transfers lipoyl group from lipoyl-GCSH to DLAT BibTex
2024-02-16 R-HSA-9855212 SDHA binds to SDHB BibTex
2024-02-16 R-HSA-9854315 CSKMT methylates Citrate Synthase BibTex
2024-02-16 R-HSA-189421 CPO transforms COPRO3 to PPGEN9 BibTex
2024-02-16 R-HSA-189425 UROD decarboxylates URO3 to COPRO3 BibTex
2024-02-16 R-HSA-189439 ALAD condenses 2 dALAs to form PBG BibTex
2024-02-16 R-HSA-190182 UROD decarboxylates URO1 to COPRO1 BibTex
2024-02-16 R-HSA-2995334 COX15 transforms heme O to heme A BibTex
2024-02-16 R-HSA-190141 ALAD binds to Pb2+ BibTex
2024-02-16 R-HSA-5690873 ACO1 binds 4Fe-4S BibTex
2024-02-16 R-HSA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region BibTex
2024-02-16 R-HSA-5690886 ACO1, IREB2 bind IREs in TFRC, ALAD, FTL, FTH1 mRNAs BibTex
2024-02-15 R-HSA-9856871 MDH1 reduces OA BibTex
2024-02-15 R-HSA-450971 NNT dimer transfers proton from NADPH to NAD+ BibTex
2024-02-15 R-HSA-450984 IDH2 dimer decarboxylates isocitrate BibTex
2024-02-15 R-HSA-70971 ACO2 isomerizes citrate BibTex
2024-02-15 R-HSA-70975 CS acetylates OA to citrate BibTex
2024-02-15 R-HSA-70979 MDH2 dimer dehydrogenates MAL BibTex
2024-02-15 R-HSA-70982 FH tetramer hydrates fumarate to L-malate BibTex
2024-02-15 R-HSA-70994 SDH complex dehydrogenates succinate BibTex
2024-02-15 R-HSA-9855252 SDHA:SDHB binds to SDHC:SDHD BibTex
2024-02-15 R-HSA-9854961 SDHAF4 binds to FAD-SDHA BibTex
2024-02-15 R-HSA-9854672 FAD attaches to SDHA BibTex
2024-02-15 R-HSA-9854984 Transfer of Fe-S clusters to SDHB BibTex
2024-02-15 R-HSA-70997 SUCLG1/A2 cleaves succinyl-CoA BibTex
2024-02-15 R-HSA-71401 OGDH dimer decarboxylates 2-OG BibTex
2024-02-15 R-HSA-70967 IDH3 complex decarboxylates isocitrate BibTex
2024-02-15 R-HSA-9853512 DLST transfers succinyl to CoA BibTex
2024-02-15 R-HSA-9853499 DLD dimer dehydrogenates dihydrolipoyl BibTex
2024-02-15 R-HSA-71775 SUCLG1/G2 cleaves succinyl-CoA BibTex
2024-02-15 R-HSA-9854415 ACAT1 tetramer acetylates IDH2 dimer BibTex
2024-02-15 R-HSA-9854463 SIRT3 deacetylates AcK-IDH2 dimer BibTex
2024-02-15 R-HSA-9854368 ROS,RNS oxidize ACO2:4Fe-4S BibTex
2024-02-15 R-HSA-9854405 Frataxin transfers Fe2+ to ACO2 BibTex
2024-02-13 R-HSA-163691 Phosphorylation of ChREBP at Serine 556 by AMPK BibTex
2024-02-12 R-HSA-163748 Transcriptional activation of AGPAT1 by ChREBP:MLX BibTex
2024-02-12 R-HSA-9856604 MLXIPL:MLX binds AGPAT1 gene promoter BibTex
2024-02-12 R-HSA-163666 Formation of ChREBP:MLX heterodimer BibTex
2024-02-12 R-HSA-400012 Acetylcholine binds Muscarinic Acetylcholine Receptor M3 BibTex
2024-02-12 R-HSA-400015 Diacylgycerol activates Protein kinase C, alpha type BibTex
2024-02-12 R-HSA-381706 GLP1R:GLP1 activates G(s) BibTex
2024-02-12 R-HSA-163669 Transcriptional activation of PKLR gene by ChREBP:MLX BibTex
2024-02-12 R-HSA-9856539 MLXIPL:MLX binds PKLR gene promoter BibTex
2024-02-12 R-HSA-163773 PKA tetramer:cAMP phosphorylates PF2K-Pase BibTex
2024-02-12 R-HSA-9856549 MLXIPL:MLX binds ACLY gene promoter BibTex
2024-02-12 R-HSA-163733 Transcriptional activation of FASN monomer gene by ChREBP:MLX BibTex
2024-02-12 R-HSA-9856546 MLXIPL:MLX binds FASN gene promoter BibTex
2024-02-12 R-HSA-163743 Transcriptional activation of ACACA by ChREBP:MLX BibTex
2024-02-12 R-HSA-9856550 MLXIPL:MLX binds ACACA gene promoter BibTex
2024-02-12 R-HSA-9856605 Transcriptional activation of ACACB by ChREBP:MLX BibTex
2024-02-12 R-HSA-9856548 MLXIPL:MLX binds ACACB gene promoter BibTex
2024-02-12 R-HSA-381707 PKA:AKAP79:IQGAP1 complex dissociates to active PKA subunits in response to cAMP BibTex
2024-02-12 R-HSA-381704 G(s):GTP activates Adenylyl cyclase BibTex
2024-02-12 R-HSA-381668 cAMP activates EPAC1 BibTex
2024-02-12 R-HSA-381608 cAMP activates EPAC2 BibTex
2024-02-12 R-HSA-400071 Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline BibTex
2024-02-12 R-HSA-400037 Gi,Go Heterotrimeric G-protein complex dissociates BibTex
2024-02-12 R-HSA-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins BibTex
2024-02-12 R-HSA-400097 G-beta:G-gamma inhibits Adenylate cyclase BibTex
2024-02-12 R-HSA-164151 LKB1 phosphorylates the alpha subunit of AMPK heterotrimer BibTex
2024-02-12 R-HSA-163672 Phosphorylation of ChREBP at Thr(653) by PKA BibTex
2024-02-12 R-HSA-163676 Phosphorylation of pChREBP (Thr 653) at Ser(196) by PKA BibTex
2024-02-12 R-HSA-1483087 PI is exchanged with PC by PITPNB BibTex
2024-02-12 R-HSA-1483229 PI:PITPNB is transported from the ER membrane to the Golgi membrane BibTex
2024-02-12 R-HSA-1483219 PC is exchanged with PI by PITPNB BibTex
2024-02-12 R-HSA-1483211 PC:PITPNB is transported from the Golgi membrane to the ER membrane BibTex
2023-11-06 R-HSA-9851407 FAM83B, (FAM83A, FAM83D) bind EGFR BibTex
2023-11-06 R-HSA-177934 EGFR autophosphorylation BibTex
2023-11-02 R-HSA-177922 EGFR dimerization BibTex
2023-07-26 R-HSA-196773 COASY phosphorylates DP-CoA BibTex
2023-07-26 R-HSA-196754 COASY transfers an adenylyl group from ATP to PPANT BibTex
2023-07-26 R-HSA-196840 3xPPCDC:3FMN decarboxylates PPC BibTex
2023-07-26 R-HSA-196753 2xPPCS ligates PPanK with Cys BibTex
2023-07-26 R-HSA-199203 PANK1/3 phosphorylate PanK BibTex
2023-07-26 R-HSA-196857 PANK2 phosphorylates PanK BibTex
2023-07-26 R-HSA-9837333 SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP BibTex
2023-07-26 R-HSA-9837337 DCAKD phosphorylates DP-CoA BibTex
2023-07-26 R-HSA-9837354 NUDT8 hydrolyzes CoA-SH to PPANT BibTex
2023-07-26 R-MMU-9837342 Nudt8 hydrolyzes CoA-SH to PPANT BibTex
2023-07-26 R-HSA-9837419 PANK4 hydrolyzes PPANT to pantetheine BibTex
2023-07-26 R-HSA-196929 FLAD1 phosphorylates FMN BibTex
2023-07-26 R-HSA-196964 RFK:Mg2+ phosphorylates RIB BibTex
2023-07-26 R-HSA-196955 2xENPP1 hydrolyzes FAD to FMN BibTex
2023-05-16 R-HSA-5652195 SORD oxidizes D-sorbitol to Fru BibTex
2023-05-16 R-HSA-70333 KHK dimer phosphorylates Fru to Fru 1-P BibTex
2023-05-16 R-HSA-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP BibTex
2023-05-16 R-HSA-6813749 ALDH1A1 oxidises GA to DGA BibTex
2023-05-16 R-HSA-6799495 GLYCTK phosphorylates DGA to 3PDGA BibTex
2022-11-18 R-HSA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P BibTex
2022-11-09 R-HSA-9820566 ZnT5 transports zinc into the golgi apparatus BibTex
2022-11-09 R-HSA-9817575 ERO1B oxidizes P4HB BibTex
2022-08-29 R-HSA-70613 GOT2 transaminates OA and L-Glu BibTex
2022-08-29 R-HSA-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp BibTex
2022-08-29 R-HSA-372448 SLC25A12,13 exchange L-Glu and L-Asp BibTex
2022-08-29 R-HSA-376851 SLC25A11 exchanges 2-OG and MAL BibTex
2022-08-29 R-HSA-198440 SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane BibTex
2022-08-29 R-HSA-372843 SLC25A10 mediates exchange of malate and phosphate BibTex
2022-08-29 R-HSA-70475 GPI dimer isomerizes Fru(6)P to G6P BibTex
2022-08-29 R-HSA-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P BibTex
2022-08-29 R-HSA-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP BibTex
2022-08-29 R-HSA-70481 TPI1 dimer isomerizes GA3P to DHAP BibTex
2022-08-29 R-HSA-70482 GAPDH tetramers reduce 1,3BPG to GA3P BibTex
2022-08-29 R-HSA-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG BibTex
2022-08-29 R-HSA-71445 PGAM dimers isomerise 2PG to 3PG BibTex
2022-08-29 R-HSA-70241 PCK1 phosphorylates OA to yield PEP BibTex
2022-08-29 R-HSA-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG BibTex
2022-08-29 R-HSA-372449 SLC25A1 may exchange mitochondrial PEP for cytosolic anion BibTex
2022-08-29 R-HSA-372819 PCK2 phosphorylates OA to yield PEP BibTex
2022-08-29 R-HSA-70501 PC carboxylates PYR to OA BibTex
2022-08-29 R-HSA-198513 SLC7A4 exchanges G6P for Pi across the ER membrane BibTex
2022-08-29 R-HSA-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) BibTex
2022-08-29 R-HSA-3257122 SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane BibTex
2022-08-29 R-HSA-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) BibTex
2022-08-29 R-HSA-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) BibTex
2022-08-29 R-HSA-198458 Efflux of Glc from the endoplasmic reticulum BibTex
2022-08-18 R-HSA-9792608 SLC35D2 exchanges UDP-D-glucose for UMP BibTex
2022-05-20 R-HSA-2024084 HS-GAGs translocate to the lysosome for degradation BibTex
2022-05-20 R-HSA-1678694 Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans BibTex
2022-05-20 R-HSA-2046239 Extracellular KSPG translocates to the lysosome for degradation BibTex
2022-05-19 R-HSA-427555 SLC26A1,2 cotransport SO4(2-), anion from extracellular region to cytosol BibTex
2022-05-19 R-HSA-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS BibTex
2022-05-19 R-HSA-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS BibTex
2022-05-19 R-HSA-741449 SLC35B2,3 exchange cytosolic PAPS with Golgi PAP BibTex
2022-02-14 R-HSA-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin BibTex
2022-02-14 R-HSA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol BibTex
2022-02-14 R-HSA-9759202 LRP2-mediated TCN2:RCbl uptake and delivery to lysosome BibTex
2022-02-14 R-HSA-9759209 LRP2 binds extracellular TCN2:RCbl BibTex
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