ALB binds extracellular heme

Stable Identifier
R-HSA-9661419
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Circulating free heme is cytotoxic. Binding of albumin (ALB) to heme protects cells from this potential toxicity (Desuzinges-Mandon et al. 2010).

Literature References
PubMed ID Title Journal Year
20705604 ABCG2 transports and transfers heme to albumin through its large extracellular loop

Desuzinges-Mandon, E, Arnaud, O, Martinez, L, Huché, F, Di Pietro, A, Falson, P

J. Biol. Chem. 2010
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