MeSebGalNac is oxidatively cleaved to MeSeO2H and 2-acetamidoglucal

Stable Identifier
R-HSA-5333612
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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MeSebGalNac is oxidatively cleaved to MeSeO2H and 2-acetamidoglucal
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1beta-methylseleno-N-acetyl-D-galactosamine (MeSebGalNac) aka selenosugar B is oxidatively cleaved to methylseleninic acid (MeSeO2H) and 2-acetamidoglucal by an unknown mechanism. The actual enzyme or enzymes involved have yet to be identified. This reaction is inferred from the event in rat (Suzuki et al. 2006).
Literature References
PubMed ID Title Journal Year
16842833 Distribution and reuse of 76Se-selenosugar in selenium-deficient rats

Suzuki, KT, Somekawa, L, Suzuki, N

Toxicol. Appl. Pharmacol. 2006
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Catalyst Activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen of unknown selenosugar oxidase [cytosol]

Physical Entity
unknown selenosugar oxidase [cytosol] (Homo sapiens)
Activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705)
Inferred From
MeSebGalNac is oxidatively cleaved to MeSeO2H and 2-acetamidoglucal (Rattus norvegicus)
Authored
Williams, MG  (2014-05-06)
Reviewed
Rush, MG  (2015-08-30)
Hill, DP  (2025-02-25)
Created
Williams, MG  (2014-02-19)
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