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MeSebGalNac is oxidatively cleaved to MeSeO2H and 2-acetamidoglucal
Stable Identifier
R-HSA-5333612
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
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Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Selenoamino acid metabolism (Homo sapiens)
Formation of selenosugars for excretion (Homo sapiens)
MeSebGalNac is oxidatively cleaved to MeSeO2H and 2-acetamidoglucal (Homo sapiens)
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1beta-methylseleno-N-acetyl-D-galactosamine (MeSebGalNac) aka selenosugar B is oxidatively cleaved to methylseleninic acid (MeSeO2H) and 2-acetamidoglucal by an unknown mechanism. The actual enzyme or enzymes involved have yet to be identified. This reaction is inferred from the event in rat (Suzuki et al. 2006).
Literature References
PubMed ID
Title
Journal
Year
16842833
Distribution and reuse of 76Se-selenosugar in selenium-deficient rats
Suzuki, KT
,
Suzuki, N
,
Somekawa, L
Toxicol. Appl. Pharmacol.
2006
Participants
Input
MeSebGalNac [cytosol]
Output
2-acetamidoglucal [cytosol]
MeSeO2H [cytosol]
Participates
as an event of
Formation of selenosugars for excretion (Homo sapiens)
Inferred From
MeSebGalNac is oxidatively cleaved to MeSeO2H and 2-acetamidoglucal (Rattus norvegicus)
Authored
Williams, MG (2014-05-06)
Reviewed
Rush, MG (2015-08-30)
Created
Williams, MG (2014-02-19)
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