PI:PITPNB is transported from the ER membrane to the Golgi membrane

Stable Identifier
R-HSA-1483229
Type
Reaction [transition]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane, Golgi membrane
ReviewStatus
5/5
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PI:PITPNB is transported from the ER membrane to the Golgi membrane
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The phosphatidylinositol transfer protein beta isoform (PITPNB) bound to phosphatidylinositol (PI) complex transports from the endoplasmic reticulum (ER) membrane to the Golgi membrane (Carvou et al. 2010, Yoder et al. 2001, Shadan et al. 2008).
Literature References
PubMed ID Title Journal Year
18636990 Dynamics of lipid transfer by phosphatidylinositol transfer proteins in cells

Shadan, S, Holic, R, Carvou, N, Ee, P, Li, M, Murray-Rust, J, Cockcroft, S

Traffic 2008
11104777 Structure of a multifunctional protein. Mammalian phosphatidylinositol transfer protein complexed with phosphatidylcholine

Yoder, MD, Thomas, LM, Tremblay, JM, Oliver, RL, Yarbrough, LR, Helmkamp GM, Jr

J Biol Chem 2001
20332109 Phosphatidylinositol- and phosphatidylcholine-transfer activity of PITPbeta is essential for COPI-mediated retrograde transport from the Golgi to the endoplasmic reticulum

Carvou, N, Holic, R, Li, M, Futter, C, Skippen, A, Cockcroft, S

J Cell Sci 2010
Participants
Input
Output
Participates
as an event of
Catalyst Activity

phosphatidylinositol transfer activity of PI:PITPNB [endoplasmic reticulum membrane]

Physical Entity
PI:PITPNB [endoplasmic reticulum membrane] (Homo sapiens)
Activity
phosphatidylinositol transfer activity (GO:0008526)
Orthologous Events
PI:PITPNB is transported from the ER membrane to the Golgi membrane (Bos taurus)
PI:PITPNB is transported from the ER membrane to the Golgi membrane (Caenorhabditis elegans)
PI:PITPNB is transported from the ER membrane to the Golgi membrane (Canis familiaris)
PI:PITPNB is transported from the ER membrane to the Golgi membrane (Danio rerio)
PI:PITPNB is transported from the ER membrane to the Golgi membrane (Dictyostelium discoideum)
PI:PITPNB is transported from the ER membrane to the Golgi membrane (Drosophila melanogaster)
PI:PITPNB is transported from the ER membrane to the Golgi membrane (Gallus gallus)
PI:PITPNB is transported from the ER membrane to the Golgi membrane (Mus musculus)
PI:PITPNB is transported from the ER membrane to the Golgi membrane (Plasmodium falciparum)
PI:PITPNB is transported from the ER membrane to the Golgi membrane (Rattus norvegicus)
PI:PITPNB is transported from the ER membrane to the Golgi membrane (Sus scrofa)
PI:PITPNB is transported from the ER membrane to the Golgi membrane (Xenopus tropicalis)
Authored
Williams, MG  (2011-10-18)
Reviewed
Wakelam, M  (2012-05-14)
Hill, DP  (2024-02-12)
Created
Williams, MG  (2011-08-12)
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