Cystathionine is cleaved to cysteine, oxobutanoate, and ammonia by the alpha,gamma-elimination activity of cystathionine gamma-lyase (CTH). CTH utilises pyridoxal 5'-phosphate (PXLP) as cofactor (Chiku et al. 2009, Steegborn et al. 1999).
Marinkovic, S, Huber, R, Steegborn, C, Sondermann, P, Wahl, MC, Clausen, T, Worbs, M, Jacob, U
Zhu, W, Chiku, T, Padovani, D, Banerjee, R, Singh, S, Vitvitsky, V
cystathionine gamma-lyase activity of PXLP-K212-CTH tetramer [cytosol]
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