Acireducone (1,2-Dihydroxy-3-oxo-5'-methylthiopentene) is oxidized using acireductone dioxygenase and dioxygen. There are two reactions possible, dependent on the metal cofactor: the alternative product 3-methylthiopropionate using nickel was confirmed in Klebsiella. In eukaryotes using iron(II) the result is 4-methylthio-2-oxobutanoate (MOB). (Ju et al, 2006)
Hedstrom, L, Cai, X, Haleem, R, Xiao, W, Pagani, GM, Jiang, F, Pochapsky, TC, Wang, Z, Stern, JA, Eggener, S, Hitchens, MR, Pins, M, Ai, J, Oram, SW
acireductone dioxygenase [iron(II)-requiring] activity of ARD:Fe++ [cytosol]
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