PXKLP-K305-CSAD decarboxylates 3-sulfinoalanine to hypotaurine

Stable Identifier
R-HSA-1655443
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Cysteine sulfinic acid decarboxylase (CSAD) mediates the decarboxylase of 3-sulfinoalanine to produce hypotuarine. CSAD functions as a homodimer and requires pyridoxal phosphate as a cofactor. Purification, characterisation and activity of CSAD has been determined from rat liver (Guion-Rain et al. 1975).

Literature References
PubMed ID Title Journal Year
236774 Rat liver cysteine sulfinate decarboxylase: purification, new appraisal of the molecular weight and determination of catalytic properties

Guion-Rain, M-C, Portemer, C, Chatagner, F

Biochim Biophys Acta 1975
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
sulfinoalanine decarboxylase activity of PXKLP-K305-CSAD dimer [cytosol]
Physical Entity
Activity
Inferred From
Cross References
Rhea
Authored
Reviewed
Created