MeSebGalNac is hydrolysed to MeSeH and bGalNac

Stable Identifier
R-HSA-5333609
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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MeSebGalNac is hydrolysed to MeSeH and bGalNac
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
1beta-methylseleno-N-acetyl-D-galactosamine (MeSebGalNac) aka selenosugar B is hydrolysed to methylselenol (MeSeH) and N-acetyl-beta-D-galactosamine (bGalNac) by an unknown mechanism. The actual enzyme or enzymes involved have yet to be identified. This reaction is inferred from the event in rat (Suzuki et al. 2006).
Literature References
PubMed ID Title Journal Year
16842833 Distribution and reuse of 76Se-selenosugar in selenium-deficient rats

Suzuki, KT, Suzuki, N, Somekawa, L

Toxicol. Appl. Pharmacol. 2006
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Output
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as an event of
Catalyst Activity

hydrolase activity, acting on glycosyl bonds of unknown selenosugar hydrolase [cytosol]

Physical Entity
unknown selenosugar hydrolase [cytosol] (Homo sapiens)
Activity
hydrolase activity, acting on glycosyl bonds (GO:0016798)
Inferred From
MeSebGalNac is hydrolysed to MeSeH and bGalNac (Rattus norvegicus)
Authored
Williams, MG  (2014-05-06)
Reviewed
Hill, DP  (2025-02-25)
Rush, MG  (2015-08-30)
Created
Williams, MG  (2014-02-19)
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