BIL binds ALB

Stable Identifier
R-HSA-9661432
Type
Reaction [binding]
Species
Homo sapiens
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The serum protein albumin (ALB) binds unconjugated bilirubin (BIL), preventing BIL toxicity (Griffiths et al. 1975, Weisiger et al. 2001). ALB-bound BIL is a water-soluble complex and is transported to the liver where it is selectively absorbed by hepatocytes.

Literature References
PubMed ID Title Journal Year
11397817 Affinity of human serum albumin for bilirubin varies with albumin concentration and buffer composition: results of a novel ultrafiltration method

Weisiger, RA, Ostrow, JD, Koehler, RK, Webster, CC, Mukerjee, P, Pascolo, L, Tiribelli, C

J. Biol. Chem. 2001
1157293 The albumin binding of unconjugated bilirubin in serum

Griffiths, WC, Diamond, I, Dextraze, P

Clin. Biochem. 1975
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