glucokinase [nucleoplasm] => glucokinase [cytosol]

Stable Identifier
R-HSA-170825
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nuclear envelope
ReviewStatus
5/5
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glucokinase [nucleoplasm] => glucokinase [cytosol]
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Free glucokinase (GCK1) leaves the nucleus via the nuclear pore. While the GCK1 protein contains a nuclear export sequence motif, the molecular details of the GCK1 export process remain to be worked out (Shiota et al. 1999).
Literature References
PubMed ID Title Journal Year
10601273 Nuclear import of hepatic glucokinase depends upon glucokinase regulatory protein, whereas export is due to a nuclear export signal sequence in glucokinase

Magnuson, MA, Grimsby, J, Shiota, C, Coffey, J, Grippo, JF

J Biol Chem 1999
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Orthologous Events
glucokinase [nucleoplasm] => glucokinase [cytosol] (Bos taurus)
glucokinase [nucleoplasm] => glucokinase [cytosol] (Caenorhabditis elegans)
glucokinase [nucleoplasm] => glucokinase [cytosol] (Canis familiaris)
glucokinase [nucleoplasm] => glucokinase [cytosol] (Drosophila melanogaster)
glucokinase [nucleoplasm] => glucokinase [cytosol] (Gallus gallus)
glucokinase [nucleoplasm] => glucokinase [cytosol] (Mus musculus)
glucokinase [nucleoplasm] => glucokinase [cytosol] (Plasmodium falciparum)
glucokinase [nucleoplasm] => glucokinase [cytosol] (Rattus norvegicus)
glucokinase [nucleoplasm] => glucokinase [cytosol] (Saccharomyces cerevisiae)
glucokinase [nucleoplasm] => glucokinase [cytosol] (Schizosaccharomyces pombe)
glucokinase [nucleoplasm] => glucokinase [cytosol] (Xenopus tropicalis)
Created
D'Eustachio, P  (2006-01-17)
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