Nicotinamide phosphoribosyltransferase (NamPRT) catalyzes the condensation of nicotinamide with 5- phosphoribosyl-1-pyrophosphate to yield nicotinamide D-ribonucleotide (NMN), an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway.
Suggs, S, McNiece, I, Stearns, G, Samal, B, Sun, Y, Xie, C
nicotinamide phosphoribosyltransferase activity of NAMPT [cytosol]
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