MTMR8 binds MTMR9

Stable Identifier
R-HSA-6809254
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
MTMR8 binds MTMR9
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
MTMR8 binds to MTMR9, an enzymatically inactive myotubularin family member, which results in increased stability and increased catalytic activity of MTMR8 (Zou et al. 2012).
Literature References
PubMed ID Title Journal Year
22647598 Myotubularin-related protein (MTMR) 9 determines the enzymatic activity, substrate specificity, and role in autophagy of MTMR8

Zou, J, Zhang, C, Marjanovic, J, Kisseleva, MV, Majerus, PW, Wilson, MP

Proc. Natl. Acad. Sci. U.S.A. 2012
Participants
Input
Output
Participates
as an event of
Catalyst Activity

phosphatase activator activity of MTMR9 [cytosol]

Physical Entity
MTMR9 [cytosol] (Homo sapiens)
Activity
phosphatase activator activity (GO:0019211)
Orthologous Events
MTMR8 binds MTMR9 (Bos taurus)
MTMR8 binds MTMR9 (Caenorhabditis elegans)
MTMR8 binds MTMR9 (Danio rerio)
MTMR8 binds MTMR9 (Dictyostelium discoideum)
MTMR8 binds MTMR9 (Drosophila melanogaster)
MTMR8 binds MTMR9 (Gallus gallus)
MTMR8 binds MTMR9 (Saccharomyces cerevisiae)
MTMR8 binds MTMR9 (Schizosaccharomyces pombe)
MTMR8 binds MTMR9 (Sus scrofa)
Authored
Orlic-Milacic, M  (2015-11-13)
Reviewed
Rush, MG  (2017-01-10)
Hill, DP  (2025-08-13)
Created
Orlic-Milacic, M  (2015-11-10)
Cite Us!