I(1,4,5)P3 transports from the cytosol to the nucleus

Stable Identifier
R-HSA-1855190
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol, nucleoplasm
ReviewStatus
5/5
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I(1,4,5)P3 transports from the cytosol to the nucleus
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Inositol 1,4,5-trisphosphate (I(1,4,5)P3) translocates from the cytosol to the nucleus via the nuclear pore (Dewaste et al. 2003, Nalaskowski et al. 2002).
Literature References
PubMed ID Title Journal Year
12747803 The three isoenzymes of human inositol-1,4,5-trisphosphate 3-kinase show specific intracellular localization but comparable Ca2+ responses on transfection in COS-7 cells

Dewaste, V, Moreau, C, De Smedt, F, Bex, F, De Smedt, H, Wuytack, F, Missiaen, L, Erneux, C

Biochem J 2003
12027805 The human homologue of yeast ArgRIII protein is an inositol phosphate multikinase with predominantly nuclear localization

Nalaskowski, MM, Deschermeier, C, Fanick, W, Mayr, GW

Biochem J 2002
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Authored
Williams, MG  (2011-10-28)
Reviewed
Hill, DP  (2025-10-08)
Created
Williams, MG  (2011-10-28)
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