RFK:Mg2+ phosphorylates RIB

Stable Identifier
R-HSA-196964
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
ATP + riboflavin => ADP + FMN + H(+)
ReviewStatus
5/5
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Phosphorylation of riboflavin (RIB) results in the formation of the first cofactor, flavin mononucleotide (FMN). This reaction is catalyzed by riboflavin kinase (RFK), a cytosolic enzyme existing as a monomer. It utilizes either zinc or magnesium ions in the reaction.
Literature References
PubMed ID Title Journal Year
12623014 Crystal structure of human riboflavin kinase reveals a beta barrel fold and a novel active site arch

Zhang, H, Osterman, AL, Karthikeyan, S, Grishin, NV, Mseeh, F, Zhou, Q

Structure 2003
Participants
Participates
Catalyst Activity

riboflavin kinase activity of RFK:Mg2+ [cytosol]

Orthologous Events
Cross References
Rhea
Reviewed
Created
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