acetyl-CoA + H2O => acetate + CoASH

Stable Identifier
R-HSA-390304
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
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Peroxisomal ACOT8 catalyzes the hydrolysis of acetyl-CoA to form acetate and CoASH (Jones et al. 1999; Wanders and Waterham 2006).

Literature References
PubMed ID Title Journal Year
10092594 Identification of peroxisomal acyl-CoA thioesterases in yeast and humans

Jones, JM, Nau, K, Geraghty, MT, Erdmann, R, Gould, SJ

J Biol Chem 1999
16756494 Biochemistry of mammalian peroxisomes revisited

Wanders, RJ, Waterham, HR

Annu Rev Biochem 2006
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
acetyl-CoA hydrolase activity of ACOT8 [peroxisomal matrix]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created
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