Reactome | atREs binds to nascent CM

atREs binds to nascent CM

Stable Identifier

R-HSA-2395764

Type

Reaction [binding]

Species

Homo sapiens

Compartment

cytosol

ReviewStatus

5/5

Locations in the PathwayBrowser

Expand all

General

SBML | | PDF

SVG | | PPTX | SBGN

Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Chylomicrons (CM) are large (75–450 nm), spherical lipoprotein particles secreted by intestinal cells postprandially and transport dietary fat and fat-soluble vitamins in the lymphatic system (Nayak et al. 2001, During & Harrison 2007). All-trans-retinyl esters (atREs) are packaged into nascent chylomicrons.

Literature References

PubMed ID	Title	Journal	Year
17644776	Mechanisms of provitamin A (carotenoid) and vitamin A (retinol) transport into and out of intestinal Caco-2 cells During, A, Harrison, EH	J Lipid Res	2007
11181758	Retinyl ester secretion by intestinal cells: a specific and regulated process dependent on assembly and secretion of chylomicrons Hussain, MM, Harrison, EH, Nayak, N	J Lipid Res	2001