SeCysta is hydrolysed to Sec by PXLP-K212-CTH

Stable Identifier
R-HSA-2408543
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
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SeCysta is hydrolysed to Sec by PXLP-K212-CTH
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Cystathionine gamma-lyase (CTH) homotetramer is involved in the hydrolysis of selenocystathionine (SeCysta) into selenocysteine (Sec), ammonia and 2-oxobutanoic acid by an alpha,gamma-elimination reaction. This reaction is inferred from the event in rat involving the protein cystathionine gamma-lyase (Cth) homotetramer (Esaki et al. 1981).

Literature References
PubMed ID Title Journal Year
6456763 Enzymatic synthesis of selenocysteine in rat liver

Esaki, N, Nakamura, T, Tanaka, H, Suzuki, T, Morino, Y, Soda, K

Biochemistry 1981
Participants
Input
Output
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
selenocystathionine gamma-lyase activity of PXLP-K212-CTH tetramer [cytosol]
Physical Entity
PXLP-K212-CTH tetramer [cytosol]
Activity
selenocystathionine gamma-lyase activity (0098606)
Inferred From
SeCysta is hydrolysed to Sec by PXLP-K211-Cth (Rattus norvegicus)
Cross References
Rhea
Authored
Williams, MG  (2014-05-06)
Reviewed
Rush, MG  (2015-08-30)
Created
Williams, MG  (2012-07-17)