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What is Reactome ?
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Proximity matching: "raf map"~4 searches for raf and map within 4 words from each other
(raf AND map) OR (name:"PTEN S170N") OR (apoptosis) OR stID:"REACT_12858.1" OR stID:"R-HSA-198344.1"
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Species
Homo sapiens (79592)
Mus musculus (52689)
Rattus norvegicus (45435)
Sus scrofa (44245)
Bos taurus (43989)
Canis familiaris (41012)
Gallus gallus (39236)
Drosophila melanogaster (35283)
Caenorhabditis elegans (30803)
Xenopus tropicalis (29275)
Danio rerio (23670)
Dictyostelium discoideum (20034)
Saccharomyces cerevisiae (13092)
Schizosaccharomyces pombe (11563)
Entries without species (7981)
Plasmodium falciparum (7730)
Severe acute respiratory syndrome coronavirus 2 (665)
Human immunodeficiency virus 1 (634)
Human SARS coronavirus (550)
Influenza A virus (488)
Human respiratory syncytial virus A (375)
Mycobacterium tuberculosis (360)
Human cytomegalovirus (354)
Clostridium botulinum (172)
Xenopus laevis (167)
Hepatitis C Virus (143)
Oryctolagus cuniculus (140)
Rotavirus (133)
Human herpesvirus 1 (99)
Escherichia coli (96)
Hepatitis B virus (78)
Infectious bronchitis virus (71)
Measles virus (66)
Bacillus anthracis (57)
Salmonella typhimurium (57)
Cricetulus griseus (56)
Neisseria meningitidis serogroup B (56)
Chlamydia trachomatis (53)
Listeria monocytogenes (46)
Leishmania major (41)
Clostridium tetani (31)
Neisseria gonorrhoeae (28)
Ovis aries (26)
Vaccinia virus (26)
Corynephage beta (25)
Meleagris gallopavo (24)
Staphylococcus aureus (22)
Cavia porcellus (21)
Human gammaherpesvirus 4 (20)
Cercopithecus aethiops (19)
Human herpesvirus 8 (19)
Human alphaherpesvirus 2 (18)
Chlorocebus sabaeus (16)
Dengue virus (14)
Hepatitis C virus genotype 2a (13)
West Nile virus (11)
Macaca mulatta (10)
Candida albicans (7)
Human papillomavirus type 16 (7)
Mycobacterium tuberculosis H37Rv (7)
Tick-borne encephalitis virus (7)
Clostridium perfringens (6)
Moloney murine leukemia virus (6)
Sindbis virus (5)
Arenicola marina (4)
Cowpox virus (4)
Leishmania mexicana (4)
Sendai virus (4)
Triticum aestivum (4)
Vigna radiata var. radiata (4)
Alphapapillomavirus 9 (3)
Hepatitis C virus subtype 1a (3)
Homarus americanus (3)
Legionella pneumophila (3)
Molluscum contagiosum virus subtype 1 (3)
Penicillium chrysogenum (3)
Rotavirus A (3)
Crithidia fasciculata (2)
Felis catus (2)
Listeria monocytogenes serotype 1/2a (1)
Toxoplasma gondii (1)
Types
Protein (232140)
Complex (107328)
Reaction (93158)
Set (44290)
Pathway (23099)
Interactor (9998)
Genes and Transcripts (6851)
Chemical Compound (3776)
Entity (2525)
Icon (2401)
DNA Sequence (1806)
Polymer (1525)
Drug (1144)
Person (949)
RNA Sequence (794)
OtherEntity (361)
SimpleEntity (83)
PositiveRegulation (63)
NegativeRegulation (35)
Cell (16)
Requirement (6)
OpenSet (4)
ChemicalDrug (3)
PositiveGeneExpressionRegulation (3)
Compartments
cytosol (151206)
plasma membrane (104742)
nucleoplasm (99770)
extracellular region (56628)
endoplasmic reticulum membrane (18037)
endoplasmic reticulum lumen (13833)
mitochondrial matrix (12518)
Golgi membrane (10646)
Golgi lumen (9599)
mitochondrial inner membrane (7656)
mitochondrial outer membrane (5014)
lysosomal lumen (3895)
endosome membrane (3455)
lysosomal membrane (3157)
nuclear envelope (2165)
peroxisomal matrix (2027)
secretory granule lumen (2019)
trans-Golgi network membrane (1893)
ficolin-1-rich granule lumen (1885)
clathrin-coated endocytic vesicle membrane (1633)
endocytic vesicle membrane (1579)
early endosome membrane (1525)
secretory granule membrane (1461)
azurophil granule lumen (1414)
endoplasmic reticulum-Golgi intermediate compartment membrane (1386)
peroxisomal membrane (1367)
ER to Golgi transport vesicle membrane (1364)
specific granule membrane (1298)
phagocytic vesicle membrane (1266)
mitochondrial intermembrane space (1126)
tertiary granule membrane (1081)
transport vesicle (1071)
platelet alpha granule lumen (1044)
ficolin-1-rich granule membrane (994)
lumenal side of endoplasmic reticulum membrane (967)
cilium (890)
photoreceptor disc membrane (863)
azurophil granule membrane (855)
cytoplasmic vesicle membrane (833)
recycling endosome membrane (798)
specific granule lumen (789)
tertiary granule lumen (767)
ciliary tip (621)
chromosome (460)
cell junction (432)
transport vesicle membrane (421)
ciliary membrane (418)
chromosome, centromeric region (407)
endosome lumen (405)
COPII-coated ER to Golgi transport vesicle (396)
endolysosome membrane (395)
endocytic vesicle lumen (393)
ciliary base (356)
lipid droplet (349)
Golgi-associated vesicle membrane (338)
phagocytic vesicle lumen (304)
smooth endoplasmic reticulum (269)
axonemal microtubule (263)
melanosome membrane (261)
cornified envelope (253)
multivesicular body lumen (232)
platelet dense granule lumen (225)
phagophore assembly site membrane (224)
late endosome membrane (223)
extracellular exosome (216)
cytoplasm (208)
platelet alpha granule membrane (199)
cytoplasmic side of plasma membrane (197)
synaptic vesicle membrane (193)
autophagosome membrane (186)
clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane (181)
phagocytic vesicle (181)
platelet dense tubular network membrane (176)
clathrin-sculpted monoamine transport vesicle membrane (172)
clathrin-coated endocytic vesicle (164)
endosome (154)
nucleolus (147)
peptidoglycan-based cell wall (138)
double membrane vesicle viral factory outer membrane (133)
sarcoplasmic reticulum membrane (132)
early endosome (131)
photoreceptor outer segment membrane (124)
endoplasmic reticulum quality control compartment (115)
lamellar body (115)
mitochondrion (114)
external side of plasma membrane (101)
basolateral plasma membrane (94)
platelet dense granule membrane (86)
melanosome lumen (84)
clathrin-sculpted glutamate transport vesicle membrane (82)
cytoplasmic side of endoplasmic reticulum membrane (80)
microtubule organizing center (79)
multivesicular body, internal vesicle membrane (79)
late endosome lumen (78)
phagolysosome (77)
endoplasmic reticulum-Golgi intermediate compartment (76)
endolysosome lumen (74)
viral envelope (73)
lamellar body membrane (62)
early endosome lumen (59)
Reaction types
binds (19236)
phosphorylates (5404)
transports (2216)
translocates (1829)
transfers (1827)
lyses (1540)
hydrolyses (1524)
ubiquitinates (1350)
cleaves (1196)
activates (946)
oxidises (945)
reduces (705)
regulates (610)
dephosphorylates (598)
exchanges (541)
hydroxylates (504)
dehydrogenates (432)
deubiquitinates (432)
transforms (285)
decarboxylates (267)
hydrates (254)
ligates (230)
synthesizes (221)
demethylates (180)
converts (173)
deacetylates (160)
isomerises (145)
inhibits (131)
transaminates (131)
deaminates (129)
dehydrates (119)
dioxygenates (94)
signals (94)
co-transports (87)
condenses (69)
inserts (56)
elongates (46)
extends (42)
desaturates (37)
sulfates (30)
initiates (24)
ribosylates (15)
unwinds (11)
combines (4)
dismutates (1)
Filtering Parameters
Species
Homo sapiens (79592)
Mus musculus (52689)
Rattus norvegicus (45435)
Sus scrofa (44245)
Bos taurus (43989)
Canis familiaris (41012)
Gallus gallus (39236)
Drosophila melanogaster (35283)
Caenorhabditis elegans (30803)
Xenopus tropicalis (29275)
Danio rerio (23670)
Dictyostelium discoideum (20034)
Saccharomyces cerevisiae (13092)
Schizosaccharomyces pombe (11563)
Entries without species (7981)
Plasmodium falciparum (7730)
Severe acute respiratory syndrome coronavirus 2 (665)
Human immunodeficiency virus 1 (634)
Human SARS coronavirus (550)
Influenza A virus (488)
Human respiratory syncytial virus A (375)
Mycobacterium tuberculosis (360)
Human cytomegalovirus (354)
Clostridium botulinum (172)
Xenopus laevis (167)
Hepatitis C Virus (143)
Oryctolagus cuniculus (140)
Rotavirus (133)
Human herpesvirus 1 (99)
Escherichia coli (96)
Hepatitis B virus (78)
Infectious bronchitis virus (71)
Measles virus (66)
Bacillus anthracis (57)
Salmonella typhimurium (57)
Cricetulus griseus (56)
Neisseria meningitidis serogroup B (56)
Chlamydia trachomatis (53)
Listeria monocytogenes (46)
Leishmania major (41)
Clostridium tetani (31)
Neisseria gonorrhoeae (28)
Ovis aries (26)
Vaccinia virus (26)
Corynephage beta (25)
Meleagris gallopavo (24)
Staphylococcus aureus (22)
Cavia porcellus (21)
Human gammaherpesvirus 4 (20)
Cercopithecus aethiops (19)
Human herpesvirus 8 (19)
Human alphaherpesvirus 2 (18)
Chlorocebus sabaeus (16)
Dengue virus (14)
Hepatitis C virus genotype 2a (13)
West Nile virus (11)
Macaca mulatta (10)
Candida albicans (7)
Human papillomavirus type 16 (7)
Mycobacterium tuberculosis H37Rv (7)
Tick-borne encephalitis virus (7)
Clostridium perfringens (6)
Moloney murine leukemia virus (6)
Sindbis virus (5)
Arenicola marina (4)
Cowpox virus (4)
Leishmania mexicana (4)
Sendai virus (4)
Triticum aestivum (4)
Vigna radiata var. radiata (4)
Alphapapillomavirus 9 (3)
Hepatitis C virus subtype 1a (3)
Homarus americanus (3)
Legionella pneumophila (3)
Molluscum contagiosum virus subtype 1 (3)
Penicillium chrysogenum (3)
Rotavirus A (3)
Crithidia fasciculata (2)
Felis catus (2)
Listeria monocytogenes serotype 1/2a (1)
Toxoplasma gondii (1)
Types
Protein (232140)
Complex (107328)
Reaction (93158)
Set (44290)
Pathway (23099)
Interactor (9998)
Genes and Transcripts (6851)
Chemical Compound (3776)
Entity (2525)
Icon (2401)
DNA Sequence (1806)
Polymer (1525)
Drug (1144)
Person (949)
RNA Sequence (794)
OtherEntity (361)
SimpleEntity (83)
PositiveRegulation (63)
NegativeRegulation (35)
Cell (16)
Requirement (6)
OpenSet (4)
ChemicalDrug (3)
PositiveGeneExpressionRegulation (3)
Compartments
cytosol (151206)
plasma membrane (104742)
nucleoplasm (99770)
extracellular region (56628)
endoplasmic reticulum membrane (18037)
endoplasmic reticulum lumen (13833)
mitochondrial matrix (12518)
Golgi membrane (10646)
Golgi lumen (9599)
mitochondrial inner membrane (7656)
mitochondrial outer membrane (5014)
lysosomal lumen (3895)
endosome membrane (3455)
lysosomal membrane (3157)
nuclear envelope (2165)
peroxisomal matrix (2027)
secretory granule lumen (2019)
trans-Golgi network membrane (1893)
ficolin-1-rich granule lumen (1885)
clathrin-coated endocytic vesicle membrane (1633)
endocytic vesicle membrane (1579)
early endosome membrane (1525)
secretory granule membrane (1461)
azurophil granule lumen (1414)
endoplasmic reticulum-Golgi intermediate compartment membrane (1386)
peroxisomal membrane (1367)
ER to Golgi transport vesicle membrane (1364)
specific granule membrane (1298)
phagocytic vesicle membrane (1266)
mitochondrial intermembrane space (1126)
tertiary granule membrane (1081)
transport vesicle (1071)
platelet alpha granule lumen (1044)
ficolin-1-rich granule membrane (994)
lumenal side of endoplasmic reticulum membrane (967)
cilium (890)
photoreceptor disc membrane (863)
azurophil granule membrane (855)
cytoplasmic vesicle membrane (833)
recycling endosome membrane (798)
specific granule lumen (789)
tertiary granule lumen (767)
ciliary tip (621)
chromosome (460)
cell junction (432)
transport vesicle membrane (421)
ciliary membrane (418)
chromosome, centromeric region (407)
endosome lumen (405)
COPII-coated ER to Golgi transport vesicle (396)
endolysosome membrane (395)
endocytic vesicle lumen (393)
ciliary base (356)
lipid droplet (349)
Golgi-associated vesicle membrane (338)
phagocytic vesicle lumen (304)
smooth endoplasmic reticulum (269)
axonemal microtubule (263)
melanosome membrane (261)
cornified envelope (253)
multivesicular body lumen (232)
platelet dense granule lumen (225)
phagophore assembly site membrane (224)
late endosome membrane (223)
extracellular exosome (216)
cytoplasm (208)
platelet alpha granule membrane (199)
cytoplasmic side of plasma membrane (197)
synaptic vesicle membrane (193)
autophagosome membrane (186)
clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane (181)
phagocytic vesicle (181)
platelet dense tubular network membrane (176)
clathrin-sculpted monoamine transport vesicle membrane (172)
clathrin-coated endocytic vesicle (164)
endosome (154)
nucleolus (147)
peptidoglycan-based cell wall (138)
double membrane vesicle viral factory outer membrane (133)
sarcoplasmic reticulum membrane (132)
early endosome (131)
photoreceptor outer segment membrane (124)
endoplasmic reticulum quality control compartment (115)
lamellar body (115)
mitochondrion (114)
external side of plasma membrane (101)
basolateral plasma membrane (94)
platelet dense granule membrane (86)
melanosome lumen (84)
clathrin-sculpted glutamate transport vesicle membrane (82)
cytoplasmic side of endoplasmic reticulum membrane (80)
microtubule organizing center (79)
multivesicular body, internal vesicle membrane (79)
late endosome lumen (78)
phagolysosome (77)
endoplasmic reticulum-Golgi intermediate compartment (76)
endolysosome lumen (74)
viral envelope (73)
lamellar body membrane (62)
early endosome lumen (59)
Reaction types
binds (19236)
phosphorylates (5404)
transports (2216)
translocates (1829)
transfers (1827)
lyses (1540)
hydrolyses (1524)
ubiquitinates (1350)
cleaves (1196)
activates (946)
oxidises (945)
reduces (705)
regulates (610)
dephosphorylates (598)
exchanges (541)
hydroxylates (504)
dehydrogenates (432)
deubiquitinates (432)
transforms (285)
decarboxylates (267)
hydrates (254)
ligates (230)
synthesizes (221)
demethylates (180)
converts (173)
deacetylates (160)
isomerises (145)
inhibits (131)
transaminates (131)
deaminates (129)
dehydrates (119)
dioxygenates (94)
signals (94)
co-transports (87)
condenses (69)
inserts (56)
elongates (46)
extends (42)
desaturates (37)
sulfates (30)
initiates (24)
ribosylates (15)
unwinds (11)
combines (4)
dismutates (1)
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