depalmitoylation of eNOS

Stable Identifier
R-HSA-203613
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Increases in intracellular calcium and calmodulin stimulate depalmitoylation of eNOS by acyl protein thioesterase 1, which displaces eNOS from the membrane. This might be a mechanism to downregulate NO production following intense stimuli.

Participants
Participates
Catalyst Activity

palmitoyl-(protein) hydrolase activity of LYPLA1 dimer [cytosol]

Orthologous Events
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