Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5)

Stable Identifier
R-HSA-2161899
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Several cytochrome P450s (CYPs) convert arachidonic acid to 8,9-, 11,12-, and 14,15-epoxyeicosatrienoic acids (8,9-, 11,12-, 14,15-EETs). The CYPs and their references are as follows: CYP1A1, CYP1A2, CYP1B1 (Choudhary et al. 2004); CYP2C8, CYP2C9 (Rifkind et al. 1995); CYP2C19 (Bylund et al. 1998, Rifkind et al. 1995); CYP2J2 (Wu et al. 1996).

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
monooxygenase activity of CYP(5) [endoplasmic reticulum membrane]
Physical Entity
Activity
Orthologous Events
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