AFMID hydrolyses NFK to L-KYN

Stable Identifier
R-HSA-71189
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
N-formylkynurenine + H2O => kynurenine + formate
Locations in the PathwayBrowser
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Cytosolic arylformamidase (AFMID) catalyzes the hydrolysis of formylkynurenine to yield formate and L-kynurenine. Human AFMID has been identified only as an open reading frame; its activity is inferred from that of its well-characterized mouse homologue (Pabarcus and Casida 2002).

Literature References
PubMed ID Title Journal Year
12007602 Kynurenine formamidase: determination of primary structure and modeling-based prediction of tertiary structure and catalytic triad.

Pabarcus, MK, Casida, JE

Biochim Biophys Acta 2002
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
arylformamidase activity of AFMID [cytosol]
Physical Entity
Activity
Inferred From
Authored