AFMID hydrolyses NFK to L-KYN

Stable Identifier
R-HSA-71189
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
Synonyms
N-formylkynurenine + H2O => kynurenine + formate
ReviewStatus
5/5
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AFMID hydrolyses NFK to L-KYN
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Cytosolic arylformamidase (AFMID) catalyzes the hydrolysis of formylkynurenine to yield formate and L-kynurenine. Human AFMID has been identified only as an open reading frame; its activity is inferred from that of its well-characterized mouse homologue (Pabarcus and Casida 2002).
Literature References
PubMed ID Title Journal Year
12007602 Kynurenine formamidase: determination of primary structure and modeling-based prediction of tertiary structure and catalytic triad.

Casida, JE, Pabarcus, MK

Biochim Biophys Acta 2002
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Output
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as an event of
Catalyst Activity

arylformamidase activity of AFMID [cytosol]

Physical Entity
AFMID [cytosol] (Homo sapiens)
Activity
arylformamidase activity (GO:0004061)
Inferred From
N-formylkynurenine + H2O => kynurenine + formate [mouse] (Mus musculus)
Authored
D'Eustachio, P  (2005-07-20)
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