CD36 (FAT) translocates palmitate from the extracellular region to the cytosol

Stable Identifier
R-HSA-434381
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

CD36 (FAT) located in the plasma membrane of pancreatic beta cells transports fatty acids such as palmitate into the cell (Noushmehr et al. 2005).

Literature References
PubMed ID Title Journal Year
15677505 Fatty acid translocase (FAT/CD36) is localized on insulin-containing granules in human pancreatic beta-cells and mediates fatty acid effects on insulin secretion

Doria, A, Noushmehr, H, Wawrowsky, KA, Farilla, L, Mlynarski, W, D'Amico, E, Abumrad, NA, Hui, H, Perfetti, R

Diabetes 2005
Participants
Participates
Catalyst Activity

long-chain fatty acid transporter activity of 4xPalmC-CD36 [plasma membrane]

Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created
Cite Us!