CD36 (FAT) translocates palmitate from the extracellular region to the cytosol

Stable Identifier
R-HSA-434381
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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CD36 (FAT) located in the plasma membrane of pancreatic beta cells transports fatty acids such as palmitate into the cell (Noushmehr et al. 2005).

Literature References
PubMed ID Title Journal Year
15677505 Fatty acid translocase (FAT/CD36) is localized on insulin-containing granules in human pancreatic beta-cells and mediates fatty acid effects on insulin secretion

Noushmehr, H, D'Amico, E, Farilla, L, Hui, H, Wawrowsky, KA, Mlynarski, W, Doria, A, Abumrad, NA, Perfetti, R

Diabetes 2005
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
long-chain fatty acid transporter activity of 4xPalmC-CD36 [plasma membrane]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created