glycogen phosphorylase (PYGB) dimer b + 2 ATP => glycogen phosphorylase (PYGB) dimer a + 2 ADP

Stable Identifier
R-HSA-453337
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
Synonyms
L-seryl-(protein) + ATP => O-phospho-L-seryl-(protein) + ADP + H(+)
ReviewStatus
5/5
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glycogen phosphorylase (PYGB) dimer b + 2 ATP => glycogen phosphorylase (PYGB) dimer a + 2 ADP
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
The phosphorylation of glycogen phosphorylase PYGB by the widely expressed form of the phosphorylase kinase complex is inferred from its activity on PGYM (Newgard et al. 1989).
Literature References
PubMed ID Title Journal Year
2667896 The family of glycogen phosphorylases: structure and function

Newgard, CB, Hwang, PK, Fletterick, RJ

Crit Rev Biochem Mol Biol 1989
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Output
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as an event of
Catalyst Activity

phosphorylase kinase activity of phosphorylase kinase complex (PHKM) [cytosol]

Physical Entity
phosphorylase kinase complex (PHKM) [cytosol] (Homo sapiens)
Activity
phosphorylase kinase activity (GO:0004689)
This event is regulated
Positively by
Regulator
Ca2+ [cytosol]
Inferred From
glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP (Homo sapiens)
Cross References
RHEA
Authored
D'Eustachio, P  (2010-01-22)
Reviewed
Hill, DP  (2025-06-02)
Created
D'Eustachio, P  (2010-01-22)
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