Reactome | Efflux of Glc from the endoplasmic reticulum

Efflux of Glc from the endoplasmic reticulum

Stable Identifier

R-HSA-198458

Type

Reaction [uncertain]

Species

Homo sapiens

Compartment

endoplasmic reticulum lumen, endoplasmic reticulum membrane, cytosol, plasma membrane, extracellular region

ReviewStatus

5/5

Locations in the PathwayBrowser

Expand all

General

SBML | | PDF

SVG | | PPTX | SBGN

Efflux of Glc from the endoplasmic reticulum

Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Glucose (Glc) generated within the endoplasmic reticulum is exported from the cell. Several mechanisms for this transport process have been proposed but experimental data remain incomplete and contradictory (e.g., Hosokawa and Thorens 2002; Fehr et al. 2005; Van Schaftingen and Gerin 2002).

Literature References

PubMed ID	Title	Journal	Year
16314530	Evidence for high-capacity bidirectional glucose transport across the endoplasmic reticulum membrane by genetically encoded fluoresence resonance energy transfer nanosensors Fehr, M, Takanaga, H, Ehrhardt, DW, Frommer, WB	Mol Cell Biol	2005
11879177	The glucose-6-phosphatase system Van Schaftingen, E, Gerin, I	Biochem J	2002
11882499	Glucose release from GLUT2-null hepatocytes: characterization of a major and a minor pathway Hosokawa, M, Thorens, B	Am J Physiol Endocrinol Metab	2002