Hypoxia-inducible lipid droplet-associated protein (HILPDA aka HIG2) was first described as a novel gene inducible by hypoxia and glucose deprivation, but its function and mechanisms of regulation remain unknown. HILPDA is a novel lipid droplet (LD) protein and stimulates intracellular lipid accumulation, which may play an important functional role in diseases associated with pathological lipid accumulation (Gimm et al. 2010, Carr & Ahima 2016).
Amann, K, Schödel, J, Knaup, KX, Hellerbrand, C, Gimm, T, Hackenbeck, T, Teschemacher, B, Warnecke, C, Wiese, M, Eckardt, KU, Deggerich, A, Wiesener, MS, Höning, S
Carr, RM, Ahima, RS
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