Caveolin-1 dissociates from eNOS:CaM:HSP90 complex

Stable Identifier
R-HSA-202144
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

HSP90 facilitates the CaM-induced displacement of caveolin from eNOS.

Literature References
PubMed ID Title Journal Year
10781589 Reconstitution of an endothelial nitric-oxide synthase (eNOS), hsp90, and caveolin-1 complex in vitro. Evidence that hsp90 facilitates calmodulin stimulated displacement of eNOS from caveolin-1.

Gratton, JP, Fontana, J, O'Connor, DS, Garcia-Cardena, G, McCabe, TJ, Sessa, WC

J Biol Chem 2000
Participants
Input
Output
Participates
as an event of
Orthologous Events
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Gallus gallus)
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Mus musculus)
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Rattus norvegicus)
Authored
Hemish, J  (2007-10-19)
Reviewed
Enikolopov, G  (2008-02-28)
Created
Hemish, J  (2007-10-19)
Cite Us!