Caveolin-1 dissociates from eNOS:CaM:HSP90 complex

Stable Identifier
R-HSA-202144
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
plasma membrane
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Caveolin-1 dissociates from eNOS:CaM:HSP90 complex
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HSP90 facilitates the CaM-induced displacement of caveolin from eNOS.

Literature References
PubMed ID Title Journal Year
10781589 Reconstitution of an endothelial nitric-oxide synthase (eNOS), hsp90, and caveolin-1 complex in vitro. Evidence that hsp90 facilitates calmodulin stimulated displacement of eNOS from caveolin-1.

Gratton, JP, Fontana, J, O'Connor, DS, Garcia-Cardena, G, McCabe, TJ, Sessa, WC

J Biol Chem 2000
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Orthologous Events
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Mus musculus)
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Rattus norvegicus)
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Xenopus tropicalis)
Authored
Hemish, J  (2007-10-19)
Reviewed
Enikolopov, G  (2008-02-28)
Created
Hemish, J  (2007-10-19)