Synthesis of GDP-mannose

Stable Identifier
R-HSA-446205
Type
Pathway
Species
Homo sapiens
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Synthesis of GDP-mannose
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GDP-mannose is the mannose donor for the first 5 mannose addition reactions in the N-glycan precursor synthesis, and also for the synthesis of Dolichyl-phosphate-mannose involved in other mannose transfer reactions. It is synthesized from fructose 6-phosphate and GTP in three steps.

Participants
Events
Participant Of
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Event Information
Go Biological Process
GDP-mannose biosynthetic process (0009298)
Orthologous Events
Synthesis of GDP-mannose (Bos taurus)
Synthesis of GDP-mannose (Caenorhabditis elegans)
Synthesis of GDP-mannose (Canis familiaris)
Synthesis of GDP-mannose (Danio rerio)
Synthesis of GDP-mannose (Dictyostelium discoideum)
Synthesis of GDP-mannose (Drosophila melanogaster)
Synthesis of GDP-mannose (Gallus gallus)
Synthesis of GDP-mannose (Mus musculus)
Synthesis of GDP-mannose (Plasmodium falciparum)
Synthesis of GDP-mannose (Rattus norvegicus)
Synthesis of GDP-mannose (Saccharomyces cerevisiae)
Synthesis of GDP-mannose (Schizosaccharomyces pombe)
Synthesis of GDP-mannose (Sus scrofa)
Synthesis of GDP-mannose (Xenopus tropicalis)
Authored
Dall'Olio, GM  (2009-11-10)
Reviewed
Gagneux, P  (2010-04-16)
Created
Jassal, B  (2009-11-10)