Sec is reduced to H2Se by PXLP-K259-SCLY dimer

Stable Identifier
R-HSA-2408524
Type
Reaction
Species
Homo sapiens
Compartment
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Selenocysteine lyase (SCLY) homodimer is involved in the reduction of selenocysteine (Sec) to hydrogen selenide (H2Se) and alanine (Ala) (Daher and Van Lente 1992).

Literature References
PubMed ID Title Journal Year
1483038 Characterization of selenocysteine lyase in human tissues and its relationship to tissue selenium concentrations

Van Lente, F, Daher, R

J Trace Elem Electrolytes Health Dis 1992
20164179 Reaction mechanism and molecular basis for selenium/sulfur discrimination of selenocysteine lyase

Hirotsu, K, Hayashi, H, Kurokawa, S, Goto, M, Omi, R, Kurihara, T, Miyahara, I, Esaki, N, Mihara, H

J. Biol. Chem. 2010
Participants
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Catalyst Activity

selenocysteine lyase activity of PXLP-K259-SCLY dimer [cytosol]

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