PGA2 is isomerised to PGC2

Stable Identifier
R-HSA-2161666
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
Synonyms
prostaglandin A2 => prostaglandin C2
ReviewStatus
5/5
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PGA2 is isomerised to PGC2
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Dehydration in the cyclopentane ring of prostaglandin E2 (PGE2) yields prostaglandin A2 (PGA2) followed by isomerization of the double bond to yield the unstable compound prostaglandin C2 (PGC2) (Straus & Glass, 2001).
Literature References
PubMed ID Title Journal Year
11301410 Cyclopentenone prostaglandins: new insights on biological activities and cellular targets

Straus, DS, Glass, CK

Med Res Rev 2001
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Catalyst Activity

isomerase activity of isomerase [cytosol]

Physical Entity
isomerase [cytosol] (Homo sapiens)
Activity
isomerase activity (GO:0016853)
Cross References
RHEA
Rhea
Authored
Williams, MG  (2012-02-24)
Reviewed
Rush, MG  (2012-11-10)
Hill, DP  (2024-08-02)
Created
Williams, MG  (2012-03-14)
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