SLC44A1 transports Cho from cytosol to mitochondrial matrix

Stable Identifier
R-HSA-6797956
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

The choline transporter-like protein 1 (SLC44A1) as an important mediator of choline transport across both the plasma membrane and the mitochondrial membrane. It is an essential step in the oxidation of Cho to betaine, which occurs in the mitochondrial matrix (Michel & Bakovic 2009).

Literature References
PubMed ID Title Journal Year
19357133 The solute carrier 44A1 is a mitochondrial protein and mediates choline transport

Michel, V, Bakovic, M

FASEB J. 2009
Participants
Participates
Catalyst Activity

choline transmembrane transporter activity of SLC44A1 [mitochondrial outer membrane]

Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created
Cite Us!