Pathway Browser

Visualize and interact with Reactome biological pathways

Analysis Tools

Merges pathway identifier mapping,
over-representation, and expression analysis

ReactomeFIViz

Designed to find pathways and network patterns related to cancer and other types of diseases

Documentation

Information to browse the database and use its principal tools for data analysis

Reactome Research Spotlight

[October 2, 2024] In the feature article of the October 2024 issue of Drug Discovery Today titled Chemical coverage of human biological pathways Kwak et al. describe the Target 2035 initiative, whose mission is to discover chemical tools for all human proteins by 2035. The authors use Reactome as the reference standard to determine the chemical coverage of human biological pathways and to outline the advantages of adopting the pathway-based rather than the proteome-based approach in guiding Target 2035 efforts.

ARCHIVE

Why Reactome

Reactome is a free, open-source, curated and peer-reviewed pathway database. Our goal is to provide intuitive bioinformatics tools for the visualization, interpretation and analysis of pathway knowledge to support basic research, genome analysis, modeling, systems biology and education. 

European Bioinformatics Institute (EMBL-EBI)
NYU Langone Health
Oregon Health & Science University
Ontario Institute for Cancer Research

The development of Reactome is supported by grants from the US National Institutes of Health (U24 HG012198) and the European Molecular Biology Laboratory.

Version 90 released on October 2, 2024

2,742

Human Pathways

15,492

Reactions

11,506

Proteins

2,053

Small Molecules

1,057

Drugs

39,318

Literature References

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