Find Reactions, Proteins and Pathways
Pathway Browser
Visualize and interact with Reactome biological pathways
Analysis Tools
Merges pathway identifier mapping,
over-representation, and expression analysis
ReactomeFIViz
Designed to find pathways and network patterns related to cancer and other types of diseases
Documentation
Information to browse the database and use its principal tools for data analysis
Reactome Research Spotlight
[October 2, 2024] In the feature article of the October 2024 issue of Drug Discovery Today titled Chemical coverage of human biological pathways Kwak et al. describe the Target 2035 initiative, whose mission is to discover chemical tools for all human proteins by 2035. The authors use Reactome as the reference standard to determine the chemical coverage of human biological pathways and to outline the advantages of adopting the pathway-based rather than the proteome-based approach in guiding Target 2035 efforts.
Why Reactome
Reactome is a free, open-source, curated and peer-reviewed pathway database. Our goal is to provide intuitive bioinformatics tools for the visualization, interpretation and analysis of pathway knowledge to support basic research, genome analysis, modeling, systems biology and education.
The development of Reactome is supported by grants from the US National Institutes of Health (U24 HG012198) and the European Molecular Biology Laboratory.
Version 90 released on October 2, 2024
2,742
Human Pathways
15,492
Reactions
11,506
Proteins
2,053
Small Molecules
1,057
Drugs
39,318
Literature References
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