Reactome | I(1,4,5)P3 transports from the ER lumen to the cytosol

I(1,4,5)P3 transports from the ER lumen to the cytosol

Stable Identifier

R-HSA-1855217

Type

Reaction [transition]

Species

Homo sapiens

Compartment

endoplasmic reticulum lumen, cytosol

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I(1,4,5)P3 transports from the ER lumen to the cytosol

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Inositol 1,4,5-trisphosphate (I(1,4,5)P3) translocates from the endoplasmic reticulum (ER) lumen to the cytosol (Caffrey et al. 1999, Chi et al. 1999).

Literature References

PubMed ID	Title	Journal	Year
9923613	The human and rat forms of multiple inositol polyphosphate phosphatase: functional homology with a histidine acid phosphatase up-regulated during endochondral ossification Caffrey, JJ, Hidaka, K, Matsuda, M, Hirata, M, Shears, SB	FEBS Lett	1999
10087200	Multiple inositol polyphosphate phosphatase: evolution as a distinct group within the histidine phosphatase family and chromosomal localization of the human and mouse genes to chromosomes 10q23 and 19 Chi, H, Tiller, GE, Dasouki, MJ, Romano, PR, Wang, J, O'keefe, RJ, Puzas, JE, Rosier, RN, Reynolds, PR	Genomics	1999

Participants

Input

I(1,4,5)P3 [endoplasmic reticulum lumen]

Output

I(1,4,5)P3 [cytosol]

Participant Of

hasEvent

IPs transport between ER lumen and cytosol

Authored

Williams, MG (2011-10-28)

Reviewed

Wundenberg, T (2012-11-07)

Created

Williams, MG (2011-10-28)