Conversion of 4,8,12-trimethyltridecanoyl-CoA to 4,8-dimethylnonanoyl-CoA

Stable Identifier
R-HSA-390276
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
peroxisomal matrix
ReviewStatus
5/5
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Conversion of 4,8,12-trimethyltridecanoyl-CoA to 4,8-dimethylnonanoyl-CoA
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The beta-oxidation of pristanoyl-CoA requires the conversion of 4,8,12-trimethyltridecanoyl-CoA to 4,8-dimethylnonanoyl-CoA (Verhoeven et al. 1998). This conversion could be mediated by two cycles of beta-oxidation but this specific reaction sequence has not been established experimentally so it is annotated here simply as conversion of 4,8,12-trimethyltridecanoyl-CoA to 4,8-dimethylnonanoyl-CoA with no other reactants and products specified.
Literature References
PubMed ID Title Journal Year
9469587 Phytanic acid and pristanic acid are oxidized by sequential peroxisomal and mitochondrial reactions in cultured fibroblasts

Verhoeven, NM, Roe, CR, Kok, RM, Roe, DS, Wanders, RJA, Jakobs, C

J Lipid Res 1998
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Event Information
Go Biological Process
fatty acid beta-oxidation (0006635)
Authored
D'Eustachio, P  (2009-03-16)
Reviewed
Jassal, B  (2009-02-27)
Hill, DP  (2024-08-02)
Created
D'Eustachio, P  (2009-01-24)
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