(PP)2-IP4 transports from the nucleus to the cytosol

Stable Identifier
R-HSA-1855220
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleoplasm, cytosol
ReviewStatus
5/5
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(PP)2-IP4 transports from the nucleus to the cytosol
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Inositol 1,5-bisdiphospho-2,3,4,6-tetrakisphosphate (1,5-(PP)2-IP4) and inositol 3,5-bisdiphospho-1,2,4,6-tetrakisphosphate (3,5-(PP)2-IP4) translocate from the nucleus to the cytosol, via the nuclear pore (Leslie et al. 2002).
Literature References
PubMed ID Title Journal Year
12121577 Cloning and characterisation of hAps1 and hAps2, human diadenosine polyphosphate-metabolising Nudix hydrolases

Leslie, NR, McLennan, AG, Safrany, ST

BMC Biochem 2002
Participants
Input
Output
Participates
as an event of
Event Information
Go Biological Process
nuclear export (0051168)
Catalyst Activity

narrow pore channel activity of Nuclear Pore Complex (NPC) [nuclear envelope]

Physical Entity
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
Activity
narrow pore channel activity (GO:0022842)
Orthologous Events
(PP)2-IP4 transports from the nucleus to the cytosol (Bos taurus)
(PP)2-IP4 transports from the nucleus to the cytosol (Caenorhabditis elegans)
(PP)2-IP4 transports from the nucleus to the cytosol (Canis familiaris)
(PP)2-IP4 transports from the nucleus to the cytosol (Danio rerio)
(PP)2-IP4 transports from the nucleus to the cytosol (Drosophila melanogaster)
(PP)2-IP4 transports from the nucleus to the cytosol (Gallus gallus)
(PP)2-IP4 transports from the nucleus to the cytosol (Mus musculus)
(PP)2-IP4 transports from the nucleus to the cytosol (Rattus norvegicus)
(PP)2-IP4 transports from the nucleus to the cytosol (Schizosaccharomyces pombe)
(PP)2-IP4 transports from the nucleus to the cytosol (Sus scrofa)
(PP)2-IP4 transports from the nucleus to the cytosol (Xenopus tropicalis)
Authored
Williams, MG  (2011-10-28)
Reviewed
Wundenberg, T  (2012-11-07)
Hill, DP  (2025-10-08)
Hill, DP  (2025-12-16)
Created
Williams, MG  (2011-10-28)
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