MTMR2 binds SBF2

Stable Identifier
R-HSA-6809793
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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MTMR2 binds SBF2
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MTMR2 dimer forms a complex with myotubularin protein SBF2 (MTMR13, an enzymatically inactive myotubularin family member) dimer. Binding to SBF2 sequesters MTMR2 from endosomal membranes to the cytosol (Berger et al. 2006).
Literature References
PubMed ID Title Journal Year
16399794 Multi-level regulation of myotubularin-related protein-2 phosphatase activity by myotubularin-related protein-13/set-binding factor-2

Berger, P, Berger, I, Schaffitzel, C, Tersar, K, Volkmer, B, Suter, U

Hum. Mol. Genet. 2006
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Output
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as an event of
Catalyst Activity

phosphatase activator activity of SBF2 homodimer [cytosol]

Physical Entity
SBF2 homodimer [cytosol] (Homo sapiens)
Activity
phosphatase activator activity (GO:0019211)
Inferred From
Mtmr2 binds Sbf2 (Mus musculus)
Authored
Orlic-Milacic, M  (2015-11-13)
Reviewed
Rush, MG  (2017-01-10)
Hill, DP  (2025-08-13)
Created
Orlic-Milacic, M  (2015-11-13)
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