Glucose phosphorylation is a central event in cellular metabolism. ADP-dependent glucokinase (ADPGK) can phosphorylate glucose (Glc) using ADP as the phosphate donor to glucose 6-phopshate (G6P). To date, it has not been established whether this phosphorylation supports a significant role in priming glucose for a metabolic fate other than glycolysis (Richter et al. 2012). Stdies of metabolic changes during T cell activation suggest a role for it there (Kaminski et al. 2012).
Kamiński, MM, Sauer, SW, Kamiński, M, Opp, S, Ruppert, T, Grigaravičius, P, Grudnik, P, Gröne, HJ, Krammer, PH, Gülow, K
Richter, S, Richter, JP, Mehta, SY, Gribble, AM, Sutherland-Smith, AJ, Stowell, KM, Print, CG, Ronimus, RS, Wilson, WR
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