Degradation of cysteine and homocysteine

Stable Identifier
R-HSA-1614558
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Degradation of cysteine and homocysteine
Click the image above or here to open this pathway in the Pathway Browser

While in humans excess methionine is converted to homocysteine, homocysteine and its transsulfuration product cysteine can be degraded to several end products, two of which, taurine and hydrogen sulfide, have uses in other biological processes (Stipanuk & Ueki 2011).

Literature References
PubMed ID Title Journal Year
20162368 Dealing with methionine/homocysteine sulfur: cysteine metabolism to taurine and inorganic sulfur

Stipanuk, MH, Ueki, I

J Inherit Metab Dis 2011
Participants
Events
Participant Of
hasEvent
Event Information
Go Biological Process
sulfur amino acid catabolic process (0000098)
Orthologous Events
Degradation of cysteine and homocysteine (Bos taurus)
Degradation of cysteine and homocysteine (Caenorhabditis elegans)
Degradation of cysteine and homocysteine (Canis familiaris)
Degradation of cysteine and homocysteine (Danio rerio)
Degradation of cysteine and homocysteine (Dictyostelium discoideum)
Degradation of cysteine and homocysteine (Drosophila melanogaster)
Degradation of cysteine and homocysteine (Gallus gallus)
Degradation of cysteine and homocysteine (Mus musculus)
Degradation of cysteine and homocysteine (Plasmodium falciparum)
Degradation of cysteine and homocysteine (Rattus norvegicus)
Degradation of cysteine and homocysteine (Saccharomyces cerevisiae)
Degradation of cysteine and homocysteine (Schizosaccharomyces pombe)
Degradation of cysteine and homocysteine (Sus scrofa)
Degradation of cysteine and homocysteine (Xenopus tropicalis)
Authored
Stephan, R  (2010-10-24)
Reviewed
D'Eustachio, P  (2011-10-13)
Created
Jassal, B  (2011-09-29)