5beta-cholestan-3alpha,7alpha,24(S)-triol is translocated from the cytosol to the mitochondrial matrix

Stable Identifier
R-HSA-193715
Type
Reaction [transition]
Species
Homo sapiens
Compartment
mitochondrial inner membrane
ReviewStatus
5/5
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5beta-cholestan-3alpha,7alpha,24(S)-triol is translocated from the cytosol to the mitochondrial matrix
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5beta-cholestan-3alpha,7alpha,24(S)-triol is transported from the cytosol to the mitochondrial matrix. The transporter that mediates its passage across the inner mitochondrial membrane is unknown: the StAR protein that performs this function for cholesterol at the start of steroid hormone biosynthesis is excluded as StAR is not expressed in liver. Other members of the START family of transporters are candidates, however (Russell 2003).
Literature References
PubMed ID Title Journal Year
12543708 The enzymes, regulation, and genetics of bile acid synthesis

Russell, DW

Annu Rev Biochem 2003
Participants
Input
Output
Participates
as an event of
Catalyst Activity

alcohol transmembrane transporter activity of unknown START protein [mitochondrial inner membrane]

Physical Entity
unknown START protein [mitochondrial inner membrane] (Homo sapiens)
Activity
alcohol transmembrane transporter activity (GO:0015665)
Authored
D'Eustachio, P  (2007-02-24)
Reviewed
D'Eustachio, P  (2007-04-30)
Hill, DP  (2025-08-12)
Created
D'Eustachio, P  (2007-02-24)
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