FDXR transfers electrons to FDX1,2 (FDX1L)

Stable Identifier
R-HSA-2395512
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Two electrons are transferred from reduced ferredoxin reductase (FDXR, adrenodoxin reductase) to two ferredoxin-1 or ferredoxin-1L (FDX1, FDX1L) molecules, each of which binds one electron. Two protons are released during the reaction.

Literature References
PubMed ID Title Journal Year
22101253 Both human ferredoxins 1 and 2 and ferredoxin reductase are important for iron-sulfur cluster biogenesis

Shi, Y, Ghosh, M, Kovtunovych, G, Crooks, DR, Rouault, TA

Biochim. Biophys. Acta 2012
20547883 Humans possess two mitochondrial ferredoxins, Fdx1 and Fdx2, with distinct roles in steroidogenesis, heme, and Fe/S cluster biosynthesis

Sheftel, AD, Stehling, O, Pierik, AJ, Elsässer, HP, Mühlenhoff, U, Webert, H, Hobler, A, Hannemann, F, Bernhardt, R, Lill, R

Proc. Natl. Acad. Sci. U.S.A. 2010
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created