5beta-cholestan-3alpha, 7alpha, 12alpha-triol is translocated from the cytosol to the mitochondrial matrix

Stable Identifier
R-HSA-192010
Type
Reaction [transition]
Species
Homo sapiens
Compartment
mitochondrial inner membrane
ReviewStatus
5/5
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5beta-cholestan-3alpha, 7alpha, 12alpha-triol is translocated from the cytosol to the mitochondrial matrix
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5beta-cholestan-3alpha,7alpha,12alpha-triol is translocated from the cytosol to the mitochondrial matrix. The transporter that mediates its passage across the inner mitochondrial membrane is unknown: the StAR protein that performs this function for cholesterol at the start of steroid hormone biosynthesis is excluded as StAR is not expressed in liver. Other members of the START family of transporters are candidates, however (Russell 2003).
Literature References
PubMed ID Title Journal Year
12543708 The enzymes, regulation, and genetics of bile acid synthesis

Russell, DW

Annu Rev Biochem 2003
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Output
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as an event of
Authored
Jassal, B  (2007-01-19)
Reviewed
D'Eustachio, P  (2007-04-30)
Created
Jassal, B  (2007-01-26)
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