tRNA(Sec) is serylated to Ser-tRNA(Sec) by SARS dimer

Stable Identifier
R-HSA-2408526
Type
Reaction
Species
Homo sapiens
Compartment
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SVG |   | PPTX  | SBGN
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The synthetic cycle of selenocysteine (Sec) synthesis starts with misacylation (serylation) of the cognate transfer RNA (tRNA) for Sec, tRNASec, with serine (Ser) by Serine--tRNA ligase (SARS) homodimer. The structural homology of tRNASec and tRNASer enables SARS to form Ser-tRNASec (Vincent et al. 1997, Amberg et al. 1996, Heckl et al. 1998).

Literature References
Participants
Participates
Catalyst Activity

selenocysteine-tRNA ligase activity of SARS dimer [cytosol]

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