GSSebGalNac is reduced and methylated to MeSebGalNac

Stable Identifier
R-HSA-5333608
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
cytosol
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GSSebGalNac is reduced and methylated to MeSebGalNac
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

1beta-glutathionylseleno-N-acetyl-D-galactosamine (GSSebGalNac) aka selenosugar A is converted into 1beta-methylseleno-N-acetyl-D-galactosamine (MeSebGalNac) aka selenosugar B by an unknown mechanism. The actual enzyme or enzymes involved have yet to be identified. This reaction is inferred from the event in rat (Kobayashi et al. 2002).

Literature References
PubMed ID Title Journal Year
12441402 Selenosugars are key and urinary metabolites for selenium excretion within the required to low-toxic range

Kobayashi, Y, Ogra, Y, Ishiwata, K, Takayama, H, Aimi, N, Suzuki, KT

Proc. Natl. Acad. Sci. U.S.A. 2002
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hasEvent
Inferred From
GSSebGalNac is reduced and methylated to MeSebGalNac (Rattus norvegicus)
Authored
Williams, MG  (2014-05-06)
Reviewed
Rush, MG  (2015-08-30)
Created
Williams, MG  (2014-02-19)