3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine

Stable Identifier
R-HSA-71217
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
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Cytosolic kynureninase catalyzes the hydrolysis of 3-hydroxy-L-kynurenine to form L-alanine and 3-hydroxyanthranilate.

Literature References
PubMed ID Title Journal Year
9180257 Cloning and recombinant expression of rat and human kynureninase.

Gatti, S, Benatti, L, Speciale, C, Mostardini, M, Avanzi, N, Cozzi, L, Kido, R, Breton, J, Okuno, E, Toné, S, Toma, S, Nakamura, M

FEBS Lett 1997
Participants
Participates
Catalyst Activity

kynureninase activity of KYNU dimer [cytosol]

Orthologous Events
Cross References
Rhea
Authored
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