Acireductone is created

Stable Identifier
R-HSA-1237129
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
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Acireductone synthase (also: enolase-phosphatase E1) catalyzes the dephosphorylation and conversion to enolate of 2,3-dioxo-5'-methylthiopentane-1-phosphate, yielding acireductone. (Wang et al, 2005)

Literature References
PubMed ID Title Journal Year
15843022 Crystal structure of human E1 enzyme and its complex with a substrate analog reveals the mechanism of its phosphatase/enolase activity

Wang, H, Pang, H, Bartlam, M, Rao, Z

J Mol Biol 2005
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
acireductone synthase activity of E1:Mg++ [cytosol]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created