CCBL1 (KAT 1) catalyzes the reaction of phenylalanine and pyruvate to form 3-(indol-3-yl)pyruvate and alanine. The active form of CCBL1 is a homodimer with one molecule of pyridoxal phosphate bound to each monomer (Baran et al. 1994; Han et al. 2009; Rossi et al. 2004). The enzyme's cytosolic localization is inferred from that of recombinant protein overexpressed in transfected cells (Perry et al. 1995).
Rossi, F, Han, Q, Li, J, Li, J, Rizzi, M
Baran, H, Okuno, E, Kido, R, Schwarcz, R
Perry, S, Harries, H, Scholfield, C, Lock, T, King, L, Gibson, G, Goldfarb, P
Han, Q, Robinson, H, Cai, T, Tagle, DA, Li, J
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