Reactome | ND2, ND3, ND6, NDUFB6 bind the MCIA complex to form a 370kDa subcomplex

ND2, ND3, ND6, NDUFB6 bind the MCIA complex to form a 370kDa subcomplex

Stable Identifier

R-HSA-6799199

Type

Reaction [binding]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

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ND2, ND3, ND6, NDUFB6 bind the MCIA complex to form a 370kDa subcomplex

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Membrane arm subunits MT-ND2, 3 and 6 and NDUFB6 associate with the assembly factors TMEM126B, NDUFAF1, ECSIT and ACAD9 (which form the MCIA complex) forming a 370kDa subcomplex (Mckenzie & Ryan 2010, Andrews et al. 2013).

Literature References

PubMed ID	Title	Journal	Year
24191001	Assembly factors for the membrane arm of human complex I Andrews, B, Carroll, J, Ding, S, Fearnley, IM, Walker, JE	Proc. Natl. Acad. Sci. U.S.A.	2013
20552642	Assembly factors of human mitochondrial complex I and their defects in disease McKenzie, M, Ryan, MT	IUBMB Life	2010