cholesterol ester + H2O -> cholesterol + fatty acid

Stable Identifier
R-HSA-163432
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol, lipid droplet
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
cholesterol ester + H2O -> cholesterol + fatty acid
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Activated rat HSL hydrolyzes cholesterol ester to yield cholesterol + fatty acid (Fredrikson et al. 1981). The human reaction has not been studied in detail, and is inferred from the well-characterized rat one.
Participants
Input
Output
Participates
as an event of
Catalyst Activity

lipase activity of phosphorylated HSL dimer:FABP4 complex [lipid droplet]

Physical Entity
phosphorylated HSL dimer:FABP4 complex [lipid droplet] (Homo sapiens)
Activity
lipase activity (GO:0016298)
Inferred From
cholesterol ester + H2O -> cholesterol + fatty acid (Rattus norvegicus)
Authored
D'Eustachio, P  (2005-05-02)
Created
D'Eustachio, P  (2005-05-02)
Cite Us!