What is Reactome?

Reactome is a curated database of pathways and reactions in human biology. Reactions can be considered as pathway ‘steps’. Reactome defines a ‘reaction’ as any event in biology that changes the state of a biological molecule. Binding, activation, translocation, degradation and classical biochemical events involving a catalyst are all reactions. Information in the database is authored by expert biologists, entered and maintained by Reactome’s team of Curators and Editorial staff. Reactome content frequently cross-references other resources e.g. NCBI, Ensembl, UniProt, KEGG (Gene and Compound), ChEBI, PubMed and GO. Inferred orthologous reactions Inferred orthologous reactions are available for 15 non-human species including mouse, rat, chicken, puffer fish, worm, fly, yeast, rice, and Arabidopsis

What is this guide For?

This guide introduces features of the Reactome website using a combination of short explanations and exercises. You will learn how to search, interpret the views, use the tools and if necessary find documentation or This email address is being protected from spambots. You need JavaScript enabled to view it. for help.

Online Tutorial

Available via the EBI Train Online system

This quick tour provides a brief introduction to Reactome knowledgebase and its various features.

Quick tour

This course provides a more detailed view of the Reactome pathway database web interface and the database content.

Exploring Pathways

This course introduces the analysis tools available via the Reactome pathway database web interface.

Analysis Tools

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