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GSSeH combines with bGalNAc derivative to form GSSebGalNac
Stable Identifier
R-HSA-5333607
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
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Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Selenoamino acid metabolism (Homo sapiens)
Formation of selenosugars for excretion (Homo sapiens)
GSSeH combines with bGalNAc derivative to form GSSebGalNac (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
1beta-methylseleno-N-acetyl-D-galactosamine (bGalNAc ) derivative combines with glutathioselenol (GSSeH) to form 1beta-glutathionylseleno-N-acetyl-D-galactosamine (GSSebGalNac) aka selenosugar A by an unknown mechanism. The actual enzyme or enzymes involved have yet to be identified. This reaction is inferred from the event in rat (Kobayashi et al. 2002).
Literature References
PubMed ID
Title
Journal
Year
12441402
Selenosugars are key and urinary metabolites for selenium excretion within the required to low-toxic range
Kobayashi, Y
,
Suzuki, KT
,
Ogra, Y
,
Takayama, H
,
Aimi, N
,
Ishiwata, K
Proc. Natl. Acad. Sci. U.S.A.
2002
Participants
Input
bGalNAc derivative [cytosol]
GSSeH [cytosol]
Output
GSSebGalNac [cytosol]
Participates
as an event of
Formation of selenosugars for excretion (Homo sapiens)
Inferred From
GSSeH combines with bGalNAc derivative to form GSSebGalNac (Rattus norvegicus)
Authored
Williams, MG (2014-05-06)
Reviewed
Rush, MG (2015-08-30)
Created
Williams, MG (2014-02-19)
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