Sec-tRNA(Sec) binds to EEFSEC:GTP

Stable Identifier
R-HSA-2408509
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
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Sec-tRNA(Sec) binds to EEFSEC:GTP
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The final product, selenocysteinyl transfer RNA (tRNA) for Sec (Sec-tRNASec) binds to selenocysteine-specific elongation factor (EEFSEC) aka SelB complexed with GTP. This complex is now ready to be delivered to the 80S ribosome. This reaction is inferred from the equivalent reaction in mouse.

Literature References
PubMed ID Title Journal Year
10970870 Characterization of mSelB, a novel mammalian elongation factor for selenoprotein translation

Fagegaltier, D, Hubert, N, Yamada, K, Mizutani, T, Carbon, P, Krol, A

EMBO J. 2000
11265756 Decoding apparatus for eukaryotic selenocysteine insertion

Tujebajeva, RM, Copeland, PR, Xu, XM, Carlson, BA, Harney, JW, Driscoll, DM, Hatfield, DL, Berry, MJ

EMBO Rep. 2000
Participants
Input
Output
Participant Of
hasEvent
Inferred From
Sec-tRNA(Sec) binds to Eefsec:GTP (Mus musculus)
Authored
Williams, MG  (2014-05-06)
Reviewed
Rush, MG  (2015-08-30)
Created
Williams, MG  (2012-07-17)